The Chemical Pregnancy

Abstract

The chemical pregnancy is an early pregnancy loss occurring shortly after implantation. 50-75% of all miscarriages are considered to be chemical pregnancies. Although the pregnancy test is positive, the fetus cannot be detected on ultrasounds; it can be asymptomatic or it can have menstrual-like cramping and bleeding. There are numerous risk factors associated with miscarriage, such as: epidemiological, genetic, anatomical, endometrial, endocrine and immune factors, infections, inherited thrombophilia and antiphospholipid syndrome. Many drugs are related with spontaneous miscarriage, significant evidence being found for nonsteroidal anti-inflammatory drugs, inhaled corticosteroids, antidepressant medication, antiepileptic and antihypertensive drugs, the artemisinin-based combination therapy and for the diclofenac/misoprostol combination. Besides the common diseases like asthma, chronic hypertension, chronic kidney disease, thyroid disorders, diabetes mellitus, polycystic ovary syndrome and rheumatoid arthritis, there was also found a higher correlation with the risk of miscarriage for the Zika Virus infection. In conclusion, chemical pregnancy is a type of early pregnancy loss which usually doesn�t need prevention, associated with multiple risk factors.

The dynamic changes in the pattern of liver function tests in pregnant obese women

“…Results of the present study showed that obese pregnant women tend to have higher values of hepatic transaminases during all 3 trimesters of pregnancy compared to normal weight pregnant women, even though it was not statistically significant. However, it should be considered that AST and ALT levels were monitored dynamically, over several days; thus, it is necessary to describe the variation pattern of the AST value (23)(24)(25)(26)(27)(28)(29). It respects the cubic model with a significance value of P= 0.01, which shows that during our follow-up, the AST values tended to increase during Q2, followed by a definite decrease.…”