The Chemistry of Allergens. XI. Properties and Composition of Natural Proteoses Isolated from Oilseeds and Nuts by the CS-1A Procedure^1,2

Peanut allergy

“…Early attempts were made to isolate peanut allergens by Spies et al using ethanoi fractionation and basic lead acetate precipitation [69]. Subsequently, a major peanut allergen designated 'Peanut I' was isolated by Sachs et al from raw, defatted, peanut meal extract [70].…”

Ber e 1 protein: the versatile major allergen from Brazil nut seeds

“…Since the late 1920s, there have been reports of manual workers in the oil milling industry (castor and cotton seed) or in the baking industry (''baker's asthma'') becoming sensitised by inhalation of air-borne particles (Atkins et al 1988;Spies et al 1951;Spies 1974). During the 1970-1980s, the major allergens implicated in those allergies were characterised as belonging to the family of the 2S albumin/amylase-protease inhibitor proteins (Spies 1974;Youle and Huang 1981) and references therein.…”

Kapok Allergens

“…Also, the 2 % extract would contain as much as The botanically related cotton fibres have, in fact, been shown to contain a dialyzablc histamine-liberator, responsible for the symptoms of byssinosis in cotton-mill workers (13,14). 5 3. Analytical Data Fractions were analyzed for protein N, hcxoses and uronic acids; the relevant data have been collected in Tabic I.…”

“…C oulson et al (4) conducted comparative studies on the anaphylactogenic properties (in guinea pigs) of the protein constituents in kapok seed, but these immunochemical data are not directly related to the problem of kapok hypersensi tivity. The proteins in kapok seed have further been studied by S pies et al (5), who also performed skin tests with their preparations in kapok-sensitive individuals.…”