2015
DOI: 10.1016/j.jpcs.2015.05.024
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The chemistry of aminoguanidine derivatives – preparation, crystal structure, thermal properties, and molecular docking studies of aminoguanidinium salts of several carboxylic acids

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Cited by 18 publications
(4 citation statements)
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“…Similarly [AgunH] + [HCOO] − assembly also exhibit asymmetric and symmetric stretching bands of the carboxylate group at 1569 cm −1 and 1350 cm −1 respectively (Figure S1b(1)).The presence of AgunH + cations in the both the salts is manifested in strong intensity peaks at 1680 and 1690 cm −1 which can be assigned to the C−N stretching vibrations. The N−N stretching frequency of hydrazinic moiety of aminoguanidinium cation is absorbed at 1103 cm −1 . The change in characteristic frequencies of parent materials compared with that of spectrum of the salts indicated molecular complex between the aminoguanidinium and carboxylates.…”
Section: Resultsmentioning
confidence: 96%
See 1 more Smart Citation
“…Similarly [AgunH] + [HCOO] − assembly also exhibit asymmetric and symmetric stretching bands of the carboxylate group at 1569 cm −1 and 1350 cm −1 respectively (Figure S1b(1)).The presence of AgunH + cations in the both the salts is manifested in strong intensity peaks at 1680 and 1690 cm −1 which can be assigned to the C−N stretching vibrations. The N−N stretching frequency of hydrazinic moiety of aminoguanidinium cation is absorbed at 1103 cm −1 . The change in characteristic frequencies of parent materials compared with that of spectrum of the salts indicated molecular complex between the aminoguanidinium and carboxylates.…”
Section: Resultsmentioning
confidence: 96%
“…Moreover in aminoguanidinium cation the NH 2 group present in the imidinium portion at the protonated guanidine is stabilized by efficient resonance with the charge ( Figure a ), and makes a multiple sites for strong charge assisted hydrogen bonding patterns . It is because of this structural significance, aminoguanidinium resulted a stable salt formation with inorganic anions (NO 3 − , H 2 PO 4 − , Cl − , and SO 4 2− etc., ) and organic anions (tartrate, oxalate, squarate, malonate, fumarate, succinate, dipicolinate, benzoate, pyridine dicarboxylate, pyrazole −3,5 dicarboxylic acids etc.,) .In most of the reported crystal structures it is noticed that most aminoguanidine is in a monoprotonated (AgunH + ) form and in two crystal structures (dinitrate and sulphate anions) it acts as a di–cation (AgunH 2 + ). It has also been noted that depending on the nature of carboxylic acids, aminoguanidine undergone condensation reaction and form a zwitter ionic salts .…”
Section: Introductionmentioning
confidence: 99%
“…Thus, in [ 61 ], the interaction of alkaloids with ChE was studied and, according to molecular modeling data, 7-epi-javaniside binds on the surface of BChE surrounded by amino acids Glu238, Arg242, Thr284, Pro359 and Pro281. According to molecular modeling data, one of the aminoguanidinium salts of carboxylic acids studied in [ 62 ] also binds on the surface of BChE in the vicinity of Val233, Glu238, Arg242 and Val288.…”
Section: Resultsmentioning
confidence: 99%
“…[9][10][11]33 The syntheses of guanidinium and/or aminoguanidinium salts of organic acids have been widely explored with a few examples of organic salts, viz. formate, 34 hemioxalate, 35 hydrogen Ltartrates, 36,37 squarates, 38,39 fumarates, [40][41][42][43] succinates, 44 oxalates, [45][46][47][48] benzoates, 49 maleates, 50,51 pyromellitate, 52 oxamate, 48 malonate, 48 sulfoacetate 48 and glutamate. 53 From our literature survey, we identified a small number of crystal structures with 6-membered heteroaromatic dicarboxylic acids; the guanidinium/aminoguanidinium salts of chelidamate dipicolinates and quinolinate [54][55][56] reveal that the guanidinium/aminoguanidinium ions in these salts exist solely in the mono-protonated form.…”
Section: Introductionmentioning
confidence: 99%