The Chemistry of Fumagillin.^1a III

Evaluation of Fumagilin-B® and other potential alternative chemotherapies against Nosema ceranae-infected honeybees (Apis mellifera) in cage trial assays

“…The alkene side chain can be removed by basic hydrolysis, yielding the alcohol, fumagillol (Tarbell et al 1961;Gochnauer and Furgala 1962;Assil and Sporns 1991). Chemical moieties such as carboxylic acids can then be coupled to fumagillol, resulting in new semisynthetic fumagillin analogues.…”

Laboratory studies on the photostability of fumagillin, the active ingredient of Fumidil B1

“…1) is an antibiotic isolated from Aspergillus fumigatus. The production and properties were first described in 1951 (Eble and Hanson, 1951;McCowen et al, 1951), and the structure was published by Tarbell et al (1961). It was first reported to be active against nosema disease of honey bees (Apis mellifera L.) in the early 1950s (Katznelson and Jamieson, 1952;Bailey, 1953a, b).…”

Chemotaxonomy and Morphology of Aspergillus Fumigatus and Related Taxa

“…Fumigati. (Waksman and Geiger, 1944) HelvoJic acid (Chain et al, 1943) AgrocIavine, chanocIavine, elymocIavine and festuc1avine (Spilsbury and Wilkinson, 1961) Fumagillin (Tarbell et al, 1960) Fumitoxin A, B, C and D (Debeaupuis and Lafont, 1978) Fumigaclavine A, Band C (Cole et al, 1977) Fumigatin and spinulosin (Anslow and Raistrick, 1938a, b) Small phenols (Turner, 1971;Turner and Aldridge, 1983) Fumitremorgin A and B (Yamazaki et al, 1971), verruculogen and TR-2 (Cole et al, 1977) Tryptiquivaline C-H, I, and J, L, M (Yamazaki et al, 1976(Yamazaki et al, , 1977(Yamazaki et al, , 1978(Yamazaki et al, , 1979 2-chloro-l,3,8-trihydroxy-6-methylanthrone, AO-l and 2-chloro-l,3,8-trihydroxy-6-hydroxymethylanthrone (Yamamoto et al, 1968), Monomethylsulochrin (Turner, 1965) Trypacidin (Balan et al, 1965) 2,6-dihydroxyphenylacetic acid (Turner and Aldridge, 1983) 4-carboxy-S,S'-dihydroxy-3,3'-dimethyldiphenyl ether (Yamamoto et al, 1972).…”