The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae

Grayer, Renée J.; Eckert, Mária; Veitch, Nigel C.; Kite, Geoffrey C.; Marin, Petar D.; Kokubun, Tetsuo; Simmonds, Monique S. J.; Paton, Alan

doi:10.1016/s0031-9422(03)00192-4

Cited by 84 publications

(91 citation statements)

References 18 publications

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“…19) Rosmarinic acid has many biological activities such as antibacterial, anti-inflammatory, and antiviral activities. Evaluations were conducted by analysis of three working standard solutions of rosmarinic acid and luteolin 5-O-β-Dglucopyranoside.…”

Section: Resultsmentioning

confidence: 99%

Phtytochemical Studies and Quantitative HPLC Analysis of Rosmarinic Acid and Luteolin 5-O-β-D-Glucopyranoside on Thymus praecox subsp. grossheimii var. grossheimii

Sevindik

Ozgen

Atila

et al. 2015

CHEMICAL & PHARMACEUTICAL BULLETIN

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Section: Resultsmentioning

confidence: 99%

Phtytochemical Studies and Quantitative HPLC Analysis of Rosmarinic Acid and Luteolin 5-O-β-D-Glucopyranoside on Thymus praecox subsp. grossheimii var. grossheimii

Sevindik

Ozgen

Atila

et al. 2015

CHEMICAL & PHARMACEUTICAL BULLETIN

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“…(Lamiaceae) submetidas a diferentes processos de secagem de diversos diterpenos (Albuquerque et al, 2007;Bhat et al, 1977;Kelecom, 1984;Kelecom et al, 1987;Tandon et al, 1977;Wang et al, 1973;Zelnik et al, 1977), além de derivados fenólicos, tais como nepetoidinas A e B (Grayer et al, 2003) e o ácido rosmarínico (Falé et al, 2009). Estudos mais recentes têm reportado seu uso como um ingrediente de alimentos funcionais e suplementos alimentares para perda e controle de peso, tendo a forskolina como principal componente (Henderson et al, 2005;Kamohara & Noparatanawong, 2013;Kamohara et al, 2015).…”

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Parâmetros de qualidade físico-químicos e avaliação da atividade antioxidante de folhas de Plectranthus barbatus Andr. (Lamiaceae) submetidas a diferentes processos de secagem

Silva

Mendes

Almeida

et al. 2016

Rev. bras. plantas med.

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Quality of the leaves of Plectranthus barbatus Andr. (Lamiaceae) dried in solar dryer and oven. This paper describes the physicochemical composition, the evaluation of the antioxidant activity by free DPPH radicals using the scavenging method, the determination of flavonoids and total phenolic compounds of ethanol, acetone and aqueous extracts of the medicinal plant Plectranthus barbatus Andr. (Lamiaceae), dehydrated in solar dryer and circulation oven at 60 °C. Water activity rates for two drying methods were below the minimum necessary for growth and toxin production of important food pathogens. Physicochemical results showed that both processes were effective in the dehydration of P. barbatus. The results demonstrated that the acetone (over) and ethanol (over and solar dryer) extracts showed the highest content of total phenols. The ethanol extract (over) showed the highest amount of flavonoids and better antioxidant activity (75.71 ± 10.57 µg L -1 ).

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“…The higher bacteriostatic character of the ethanolic extracts of O. gratissimum is consistent with previous findings using other methodologies (Passos et al, 2009). The differences detected in the bacteriostatic activity of the extracts seem to be a consequence of the synergistic or antagonistic action of eugenol and other constituents, such as oleanolic acid, flavonoids and caffeic acid esters (Njoku et al, 1997;Grayer et al, 2003). This hypothesis can be partially confirmed by the absence of correlation between the eugenol content and the bacteriostatic activity.…”

Section: Discussionmentioning

confidence: 86%

Influence of extraction method on antibacterial activity of ethanolic extracts of Ocimum gratissimum L.

Lenise¹,

Clarissa²,

Luiz³

et al. 2015

J. Med. Plants Res.

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The aim of this study was to define whether novel extraction methods such as microwave and ultrasound could obtain the most effective ethanolic extracts of Ocimum gratissimum as antibacterial agents. These extracts were compared with respect to extractive yield, eugenol content, antibacterial activity and brine-shrimp (Artemia salina) toxicity with extracts obtained by the classical procedures of maceration and Soxhlet. Significant differences among the extracts were observed in all analyses. Soxhlet extraction gave the highest yield (19.5%). Maceration and microwave extracts yielded the highest eugenol contents (11.6 and 11.8%, respectively). The bactericidal activity of the extracts was correlated with eugenol content (r s = 0.894). Maceration gave the extract with the broadest spectrum of activity. Ultrasound methods yielded an efficient extract for use as a topical antiseptic (minimum inhibitory concentration (MIC) = 0.66 to 1.32 mg/ml for Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA)). The most active extracts to treat vancomycin-resistant enterococci (VRE) infections were obtained by Soxhlet and microwave (MIC = 5.28 mg/ml). The extract obtained by maceration was the most toxic for brine shrimp, followed by the extracts obtained by ultrasonic horn, ultrasonic cleaning bath and Soxhlet /microwave. In conclusion, the antibacterial results showed that the extractive methodology can be chosen according to the intended use.

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The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae

Cited by 84 publications

References 18 publications

Phtytochemical Studies and Quantitative HPLC Analysis of Rosmarinic Acid and Luteolin 5-<i>O</i>-β-D-Glucopyranoside on <i>Thymus praecox</i> subsp. <i>grossheimii</i> var. <i>grossheimii</i>

Phtytochemical Studies and Quantitative HPLC Analysis of Rosmarinic Acid and Luteolin 5-<i>O</i>-β-D-Glucopyranoside on <i>Thymus praecox</i> subsp. <i>grossheimii</i> var. <i>grossheimii</i>

Parâmetros de qualidade físico-químicos e avaliação da atividade antioxidante de folhas de Plectranthus barbatus Andr. (Lamiaceae) submetidas a diferentes processos de secagem

Influence of extraction method on antibacterial activity of ethanolic extracts of Ocimum gratissimum L.

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