The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB

Fine, Jo David; Eady, R.A.J.; Bauer, Eugene A.; Bauer, Johann; Bruckner‐Tuderman, Leena; Heagerty, Adrian; Hintner, Helmut; Hovnanian, Alain; Jonkman, Marcel F.; Leigh, Irene M.; McGrath, John A.; Mellerio, Jemima E.; Murrell, Dédée F.; Shimizu, Hiroshi; Uitto, Jouni; Vahlquist, Anders; Woodley, David T.; Zambruno, Giovanna

doi:10.1016/j.jaad.2008.02.004

Cited by 827 publications

(904 citation statements)

References 45 publications

Supporting

Mentioning

808

Contrasting

Unclassified

Order By: Relevance

“…2A) (23), we anticipated a potentially greater contribution of BM-derived cells in the regenerating epithelia of the engrafted Col 7-null mouse skin. The engrafted Col 7-null mouse skin initially showed extensive subepidermal detachment, similar to the skin pathology seen in human patients with RDEB (21). At 4 wk after the engraftment, we noted an even greater contribution of GFP-positive cells expressing keratinocytespecific keratins in the regenerating epidermis and hair follicles of the engrafted Col 7-null mouse skin (Fig.…”

Section: Resultssupporting

confidence: 74%

PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

Tamai

Yamazaki

Chino

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

220

201

View full text Add to dashboard Cite

The role of bone marrow cells in repairing ectodermal tissue, such as skin epidermis, is not clear. To explore this process further, this study examined a particular form of cutaneous repair, skin grafting. Grafting of full thickness wild-type mouse skin onto mice that had received a green fluorescent protein-bone marrow transplant after whole body irradiation led to an abundance of bone marrow-derived epithelial cells in follicular and interfollicular epidermis that persisted for at least 5 mo. The source of the epithelial progenitors was the nonhematopoietic, platelet-derived growth factor receptor α-positive (Lin − /PDGFRα + ) bone marrow cell population. Skin grafts release high mobility group box 1 (HMGB1) in vitro and in vivo, which can mobilize the Lin − /PDGFRα + cells from bone marrow to target the engrafted skin. These data provide unique insight into how skin grafts facilitate tissue repair and identify strategies germane to regenerative medicine for skin and, perhaps, other ectodermal defects or diseases.

show abstract

Section: Resultssupporting

confidence: 74%

PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

Tamai

Yamazaki

Chino

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

220

201

View full text Add to dashboard Cite

show abstract

“…Examples are the PPKs, which sometimes show nonacral involvement, eg, Vohwinkel keratoderma 127 caused by a particular dominant GJB2 mutation (connexin 26), 128 Mal de Meleda 129 caused by recessive SLURP1 mutations, 130 and Papillon-Lefèvre syndrome 131 caused by recessive CTSC mutations encoding cathepsin C. 132 Mutations in keratin 5 or 14 cause epidermolysis bullosa simplex, 133,134 which can present with severe neonatal blistering clinically indistinguishable from EI. 62,65,135 Importantly, hypohidrosisea common symptom in ichthyoses, especially ARCI 136 erepresents one main criterion for the heterogeneous group of the ectodermal dysplasia. 137,138 Generalized erythroderma with scaling, and even collodion membranes, have been described in single cases of hypohidrotic ectodermal dysplasia.…”

Section: Other Diseases Considered In the Classification Of Inheritedmentioning

confidence: 99%

Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009

Oji

Tadini

Akiyama

et al. 2010

Journal of the American Academy of Dermatology

Self Cite

687

704

View full text Add to dashboard Cite

“…Kindler syndrome has only recently been added as part of the classification of EB 58 . Only few case reports of patients with Kindler syndrome describe their oral features 34,[85][86][87][88][89][90] .…”

Section: Kindler Syndromementioning

confidence: 99%

“…Classification schemes were first introduced by Pearson in 1962 92 . Since then, various consensus classifications have been published 58,93,94 .…”

Section: General Information On Epidermolysis Bullosamentioning

confidence: 99%

See 1 more Smart Citation

Oral Health Care for Patients with Epidermolysis Bullosa ‐ Best Clinical Practice Guidelines

Krämer

Serrano

Zillmann

et al. 2012

Int J Paed Dentistry

View full text Add to dashboard Cite

International Journal of Paediatric Dentistry 2012; 22 (Suppl. 1): 1–35 Objective. To provide the users with information on the current best practices for managing the oral health care of people living with EB. Methods. A systematic literature search, in which the main topic is dental care in patients with Epidermolysis Bullosa, was performed. Consulted sources, ranging from 1970 to 2010, included MEDLINE, EMBASE, CINAHL, The Cochrane Library, DARE, and the Cochrane controlled trials register (CENTRAL). In order to formulate the recommendations of the selected studies the SIGN system was used. The first draft was analysed and discussed by clinical experts, methodologists and patients representatives on a two days consensus meeting. The resulting document went through an external review process by a panel of experts, other health care professionals, patient representatives and lay reviewers. The final document was piloted in three different centres in United Kingdom, Czech Republic and Argentina. Results. The guideline is composed of 93 recommendations divided into 3 main areas: 1) Oral Care ‐ access issues, early referral, preventative strategies, management of microstomia, prescriptions and review appointments‐, 2) Dental treatment: general treatment modifications, radiographs, restorations, endodontics, oral rehabilitation, periodontal treatment, oral surgery and orthodontics‐, and 3) Anaesthetic management of dental treatment. Conclusions. A preventive protocol is today's dental management approach of choice.

show abstract

The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB

Cited by 827 publications

References 45 publications

PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009

Oral Health Care for Patients with Epidermolysis Bullosa ‐ Best Clinical Practice Guidelines

Contact Info

Product

Resources

About