The Clinical and Angiographic Outcomes of Postdilation after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis

Li, Yan; Liang, Xi-Ying; Zhang, Wenjiao; Qiao, Xin; Wang, Zhilu

doi:10.1155/2021/6699812

Cited by 3 publications

(3 citation statements)

References 44 publications

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“…Another interesting observation is the reduced death risk in the case of patients with NC balloon post-dilatation after stent deployment. To date, post-dilatation with an NC balloon after stent implantation in the setting of primary PCA has been a controversial and unclear issue [ 46 ]. In the literature, it is possible to find reports relevant to long-term benefits connected with stent post-dilatation during primary PCA in the course of STEMI [ 47 ]; however, there are no similar reports relevant to the risk of in-hospital death.…”

Section: Discussionmentioning

confidence: 99%

Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study

Gawiński

Burzyńska

Marczak

et al. 2023

IJERPH

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Technological progress, such as the launching of a new generation of drug-coated stents as well as new antiplatelet drugs, has resulted in the treatment of myocardial infarction (MI) becoming much more effective. The aim of this study was to assess in-hospital mortality and to conduct an assessment of risk factors relevant to the in-hospital death of patients with MI. This study was based on an observational hospital registry of patients with MI (ACS GRU registry). For the purpose of the statistical analysis of the risk factors of death, a univariate logistic regression model was applied. In-hospital general mortality amounted to 7.27%. A higher death risk was confirmed in the following cases: (1) serious adverse events (SAEs) that occurred during the procedure; (2) patients transferred from another department of a hospital (OR = 2.647, p = 0.0056); 3) primary percutaneous coronary angioplasty performed on weekdays between 10 p.m. and 8 a.m. (OR = 2.540, p = 0.0146). The influence of workload and operator experience on the risk of death in a patient with MI has not been confirmed. The results of this study indicate the increasing importance of new risk factors for in-hospital death in patients with MI, such as selected logistical aspects of the MI treatment process and individual SAEs.

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Section: Discussionmentioning

confidence: 99%

Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study

Gawiński

Burzyńska

Marczak

et al. 2023

IJERPH

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“…Therefore, the surgery is only a starting point, 8 albeit one that improves patients’ chances of survival. 9 In addition, patients often need to take a large number of drugs for a long time after surgery, which can be a heavy financial burden to the patients’ families and society. 10 As a result, negative emotions such as anxiety and depression are common in patients with coronary heart disease after PCI, which adversely affects the recovery rate of patients after surgery.…”

Section: Introductionmentioning

confidence: 99%

“…Each object corresponds to a related symptom and is scored on a scale of 0 to 3, of which 1, 2, 5, 12, 13 and 17 are positive scores. The twelve items 3,4,6,7,8,9,10,11,14,15,16…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Negative Emotions Exhibited in Patients with Coronary Heart Disease After PCI and Any Influencing Factors

Yang¹,

Xie²,

Cai³

et al. 2022

PRBM

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Purpose To understand existing negative emotions in patients with coronary heart disease after percutaneous coronary stent implantation (PCI) and analyse its influencing factors. Methods Patients with coronary heart disease after PCI in three tertiary hospitals in Changsha City from April to September 2018 were selected as the research subjects. The self-designed general information questionnaire assessed irritability, depression and anxiety (IDA) on a self-rating scale. It was used to examine patients’ existing negative emotions with coronary heart disease after PCI and analyse the influencing factors. Results 203 questionnaires were distributed, and 202 valid questionnaires were recovered, with an effective recovery rate of 99.5%. The IDA score of patients with coronary heart disease after PCI was 17.01±7.60 points, the incidence of negative emotions was 63.8%, and the incidences of depression, anxiety and irritability were 39.6%, 8.4% and 15.8%, respectively. Negative emotion was taken as the dependent variable and a patient’s general data, such as lifestyle and disease, as the independent variables. A univariate analysis was conducted to obtain gender, age, educational level, marital status, work status, per capita monthly household income, sleep status, etc. Seven factors were identified as the influencing factors of negative emotions in patients with coronary heart disease after PCI, and the difference was statistically significant (P<0.05). Conclusion Most patients with coronary heart disease after PCI tend to exhibit negative emotions such as anxiety and depression. Medical staff should attach great importance to evaluating any negative feelings in this group and take timely targeted intervention measures to prevent and mitigate the occurrence and development of these adverse emotions in patients with coronary heart disease after PCI.

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Postdilatation after stent deployment during primary percutaneous coronary intervention: a systematic review and meta-analysis

Putra,

Widodo,

Putra

et al. 2024

Postgraduate Medical Journal

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Background The utilization of postdilatation in primary percutaneous coronary intervention (PCI) is feared to induce suboptimal coronary blood flow and compromise the outcome of the patients. This meta-analysis sought to verify whether postdilatation during primary PCI is associated with worse angiographic or long-term clinical outcomes. Methods Systematic literature searches were conducted on PubMed, The Cochrane Library, ClinicalTrials.gov, EBSCO, and Europe PMC on 10 March 2024. Eligible studies reporting the outcomes of postdilatation among ST-segment elevation myocardial infarction patients were included. The primary outcome was no-reflow condition during primary PCI based on angiographic finding. The secondary clinical outcome was major adverse cardiovascular events (MACEs) comprising all-cause death, myocardial infarction, target vessel revascularization (TVR), and stent thrombosis. Results Ten studies were finally included in this meta-analysis encompassing 3280 patients, which was predominantly male (76.6%). Postdilatation was performed in 40.7% cases. Postdilatation was associated with increased risk of no-reflow during primary PCI [Odd Ratio (OR) = 1.33, 95% Confidence Interval (CI): 1.12–1.58; P = .001)]. Conversely, postdilatation had a tendency to reduce MACE (OR = 0.70, 95% CI: 0.51–0.97; P = .03) specifically in terms of TVR (OR = 0.41, 95% CI: 0.22–0.74; P = .003). No significant differences between both groups in relation to mortality (OR = 0.58, 95% CI: 0.32–1.05; P = .07) and myocardial infarction (OR = 1.5, 95% CI: 0.78–2.89; P = .22). Conclusions Postdilatation after stent deployment during primary PCI appears to be associated with an increased risk of no-reflow phenomenon after the procedure. Nevertheless, postdilatation strategy has demonstrated a significant reduction in MACE over the course of long-term follow-up. Specifically, postdilatation significantly decreased the occurrence of TVR. Key messages: What is already known on this topic? Optimizing stent deployment by performing postdilatation during percutaneous coronary intervention (PCI) is essential for long-term clinical outcomes. However, its application during primary PCI is controversial due to the fact that it may provoke distal embolization and worsen coronary blood flow. What this study adds? In this systematic review and meta-analysis of 10 studies, we confirm that postdilatation during primary PCI is associated with worse coronary blood flow immediately following the procedure. On the contrary, this intervention proves advantageous in improving long-term clinical outcomes, particularly in reducing target vessel revascularization. How this study might affect research, practice, or policy? Given the mixed impact of postdilatation during primary PCI, this strategy should only be applied selectively. Future research should focus on identifying patients who may benefit from such strategy.

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The Clinical and Angiographic Outcomes of Postdilation after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome: A Systematic Review and Meta-Analysis

Cited by 3 publications

References 44 publications

Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study

Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study

Investigation of the Negative Emotions Exhibited in Patients with Coronary Heart Disease After PCI and Any Influencing Factors

Postdilatation after stent deployment during primary percutaneous coronary intervention: a systematic review and meta-analysis

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