The Clinical and Serological Profile of Pediatric Dengue

Ramabhatta, Sujatha; Palaniappan, Saravanan; Hanumantharayappa, Navya; Begum, Shaik Vajidunnisa

doi:10.1007/s12098-017-2423-0

Cited by 16 publications

(21 citation statements)

References 17 publications

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“…Other widelyrecognisedsymptoms were arthralgia, abdomen pain and headache. This symptom pattern is similar to those reported in several studies [17,18]. Tourniquet test was positive only in few cases.…”

Section: Discussionsupporting

confidence: 91%

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A study of clinical and laboratory profiles of dengue fever in children

Anand

Sagayaraj

et al. 2018

Int J Pediatr Res

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Background: Early recognition of characteristic clinical and laboratory parameters of is importantto facilitate prompt diagnosis andtreatmentfor a better outcome, particularly in dengue burden countries. Methods: Children aged less than 15 years who sought medical care in the pediatric department of Saveetha medical college, diagnosed as Probable Dengue/Dengue fever/ dengue with warning sign/severe dengue according to standard guidelines during the study period (July 2017-December 2017) comprised the study sample. Results: A total of 61 cases were enrolled, of these 36 were boys. The mean age was 6.49 years. Only five patients had severe dengue. Fever (96.7%), loss of appetite (59%), cough and running nose (33%) were common symptoms noted and itching (37.7%) was common during recovery. Only 11.4% of children had bleeding manifestation. Hepatomegaly was noticed in 35 children. Five children went into shock, 2 of whom had hypotension. NS1 was positive in 49%, IgM in 36%, and IgG in 13%. NS1 positivity rate on day 4, day 5 and day 6 of illness were 62.5%, 38.4% and 18.1% respectively. Conclusion: Dengue fever is common during monsoon season, and the course and severity are highly variable. Though the manifestations of dengue are similar to other viral infections, morbidity and mortality are more, thus requiring early diagnosis. As observed in our study the presence of prodromal respiratory symptoms does not preclude the diagnosis of dengue. There should be a high index of suspicion of co-infection, notablymalaria and scrub typhus, if there is an unusual persistence of fever.

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Section: Discussionsupporting

confidence: 91%

“…Similar male preponderance was noted in other studies which may be attributed to the presence of more exposed area leading to more significant chance of mosquito-borne diseases [15,16]. Majority of the children belonged to the 6-12 age group which was also reported in other studies [15,17].…”

Section: Discussionsupporting

confidence: 87%

A study of clinical and laboratory profiles of dengue fever in children

Anand

Sagayaraj

et al. 2018

Int J Pediatr Res

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“…These patients were evaluated with the recomLine Tropical Fever IgG and IgM tests, immunoblot of German origin that has a sensitivity for IgG of 100% for primary infection by Zika, 100% for secondary infection for dengue or Zika, and 98.6% for primary infection by dengue; also the IgM has a sensitivity of 72.7% for dengue or Zika, and both tests have a specificity of 96-100%. On the other hand, the mentioned test describes a sensitivity and specificity of 100% for both IgM and IgG for chikungunya's diagnosis [44].…”

Section: Diagnosis Of Dengue and Other Arbovirosis In The Context Of mentioning

confidence: 99%

Situation of Dengue after the Phenomenon of the Coastal El Niño

Díaz-Vélez¹,

Fernández-Mogollón²,

Cabrera-Enríquez³

et al. 2020

Dengue Fever in a One Health Perspective

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Coastal El Niño is a weather phenomenon that is caused by abnormal warming (above 0.4°C) of the Pacific Ocean waters near the coasts of Ecuador and Peru, and it can even reach the central and southern Peruvian coast. As a result of the climatic phenomenon, the Aedes aegypti vector (which in turn is a vector of chikungunya and Zika fever) had been quickly installed in 448 districts of Peru, and emergency was declared in 10 regions, which reported 231,874 victims; 1,129,013 affected and 143 dead. It is necessary to know this, because the direct impact of the weather phenomena contributes to the dengue vector conditioning, facilitating its dissemination with ease. The geographical and climatic conditions of the cities most affected by the El Niño Costero phenomenon turned them into zones of epidemics; in these places, there is an important population growth, from urbanization to sectorization in young towns and urban slums, where in many there is no basic infrastructure and water supply is insufficient, which requires temporary water storage, as well as high temperatures, migratory movement, and beaches with influx of people, which make not only dengue proliferate but also other arbovirosis such as chikungunya.

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“…Cough is prevalent in patients with pleural effusion or ARDS. Although rare in the pediatric population, bleeding of skin and mucosal surfaces is common in children with more severe disease . Infants aged 4‐9 months and children aged 5‐7 years are at higher risk of severe disease, and as with adults, secondary DENV infection is a risk factor for severity .…”

Section: Dengue Virusmentioning

confidence: 99%

Emerging arboviruses and implications for pediatric transplantation: A review

Freeman

Coyne

Green

et al. 2018

Pediatric Transplantation

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Recent years have brought a rise in newly emergent viral infections, primarily in the form of previously known arthropod-transmitted viruses that have increased significantly in both incidence and geographical range. Of particular note are DENV, CHIKV, and ZIKV, which are transmitted mostly by Aedes species of mosquitoes that exhibit a wide and increasing global distribution. Being important pathogens for the general population, these viruses have the potential to be devastating in the international transplant community, with graft rejection and death as possible outcomes of infection. In this review, we discuss the current state of knowledge for these viruses as well as repercussions of infection in the solid organ and HSCT population, with a focus, when possible, on pediatric patients. K E Y W O R D S arboviruses, chikungunya virus, dengue virus, pediatric transplantation, transplantation, Zika virus 2 of 12 |

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The Clinical and Serological Profile of Pediatric Dengue

Abstract: There is a considerable overlap in the symptomatology of dengue with warning signs and severe dengue. More studies are required on the severity and type of response to treatment in infants and obese adoloscents with severe dengue.

Cited by 16 publications

References 17 publications

A study of clinical and laboratory profiles of dengue fever in children

A study of clinical and laboratory profiles of dengue fever in children

Situation of Dengue after the Phenomenon of the Coastal El Niño

Emerging arboviruses and implications for pediatric transplantation: A review

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