The Clinical Implications of Bilateral Microphthalmos With Cyst

A case of microphthalmos with cyst and partial trisomy 22

“…1,2 Numerous case reports can be found on microphthalmos with cyst. Most cases, however, are sporadic and genetic abnormalities associated with this condition are limited.…”

Microphthalmia with Huge Cyst: A Simple Technique for Excision

“…(2) A cyst that is large enough to be clinically obvious associated with a microphthalmic eye; (3) A huge cyst that deforms surrounding tissues and associated with an eye so small that it may not be clinically detectable (Foxman and Cameron, 1984).…”

“…It is the least common type of microphthalmia and it is unilateral in 70% of cases (Foxman and Cameron, 1984). It occurs when the ocular embryonic fissure fails to close at the 4-week stage.…”

“…As the inner layer differentiates into retinal tissue and everts, fluid accumulates, forming the cystic space (Traboulsi, 1998). The cyst may be so small that is not detectable clinically or too large that deforms the surrounding tissues and associated with a rudimentary eye that it is not clinically detectable (Foxman and Cameron, 1984).…”

Bilateral microphthalmos and orbital cyst

“…1 It is usually unilateral with bilateral cases observed rarely. 2,4,5 The vision is usually poor. Although the exact frequency is unknown, bilateral microphthalmos with orbital cyst can be associated with systemic abnormalities involving the central nervous system, renal, cardiovascular systems or chromosomal deletions, whereas unilateral cases usually are not associated with systemic abnormalities.…”