The Clinical Profile and Surgical Treatment of Tetralogy of Fallot in the Adult: Results of Repair in 200 Patients

John, Stanley; Kejriwal, Nand; Ravikumar, Edwin; Bashi, V. V.; Mohanty, Bipin Bihari; Sukumar, I P

doi:10.1016/s0003-4975(10)63028-7

Cited by 33 publications

(32 citation statements)

References 24 publications

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“…The effect of a transannular patch in pediatric patients has been studied extensively, 20,21 but the literature is limited for adult TOF. John et al 5 had used a transannular patch in 75% of their adult TOF patients, 97% of whom were in NYHA class I. In our 10-year follow-up, there was no increase in the mortality or morbidity with the use of the transannular patch.…”

Section: Early Mortality and Morbiditymentioning

confidence: 45%

“…5,19 Seven of our patients (2.4%) required permanent pacemakers. The effect of a transannular patch in pediatric patients has been studied extensively, 20,21 but the literature is limited for adult TOF.…”

Section: Early Mortality and Morbiditymentioning

confidence: 88%

“…Traditionally, the outcome of surgery was determined in terms of survival or the New York Heart Association (NYHA) functional class. [5][6][7] However, there has been an increasing realization that mere survival is not an ideal indicator of patient well-being. Quality of life (QOL) indicators, such as social, environmental, emotional, and even religious factors, should be considered when assessing the long-term outcome following cardiac surgery.…”

Section: Introductionmentioning

confidence: 99%

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Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up

Bisoi

Murala

Airan

et al. 2007

Gen Thorac Cardiovasc Surg

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Section: Early Mortality and Morbiditymentioning

confidence: 45%

Section: Early Mortality and Morbiditymentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up

Bisoi

Murala

Airan

et al. 2007

Gen Thorac Cardiovasc Surg

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“…25,26 and the development later in life of pulmonary vascular hypertension and pulmonary venous congestion with consequent hemoptysis. 27,28 Patients in the Other group experienced 17% of the hemoptysis episodes, 40% of which occurred in children Ͻ5 years of age and 38% of which occurred in children Ͼ10 years of age. Among the several etiologies of hemoptysis in this group of patients, pneumonia was the most frequent cause accounting for 31% of the episodes.…”

Section: Discussionmentioning

confidence: 99%

Hemoptysis: A 10-Year Retrospective Study

Coss‐Bu¹,

Sachdeva²,

Bricker³

et al. 1997

Pediatrics

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ABSTRACT. Background. Hemoptysis is uncommon in pediatric practice. We reviewed 10 years of experience with hemoptysis in a tertiary pediatric hospital to identify patient characteristics and predictors of mortality.Methods. Patients were divided into four age groups (0 to 5, 6 to 10, 11 to 20, and >20 years). Hemoptysis was defined as mild (<150 mL/day), large (150 to 400 mL/day), or massive (>400 mL/day). Fever was defined as 38.5°C.Results. A total of 228 patients (115 males and 113 females) with 246 episodes of hemoptysis were identified and grouped according to primary diagnosis. There were 149 patients in the cystic fibrosis (CF) group, 37 in the congenital heart disease (CHD) group, and 42 in the Other group. Age was significantly higher in the CF group compared with the CHD and Other groups. Length of stay was significantly prolonged in the CF group compared with the Other group. The overall mortality was 13%. After initial analysis, mortality predictors were age, amount of hemoptysis, receipt of blood products, and fever. After stratification, we found: 1) in the >20-year age group, there was a difference in mortality when comparing CF patients with CHD patients; 2) for patients who received blood products, there were differences in mortality in patients with CF, CHD, and Other diagnoses; 3) for patients who received blood, there were differences in mortality only for the 0-to 5-year age group; and 4) the amount of hemoptysis was predictive for mortality only in CHD patients.Conclusions. Hemoptysis presented in young adult CF patients and in adolescent CHD patients. Young adult CF patients with hemoptysis had a higher risk of mortality compared with young adult CHD patients.

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“…15) Total correction of TOF can be performed safely in adults with low mortality, however, there have been few reports in patients over 60 years of age. 4,[16][17][18][19][20][21] Our report describes the unique clinical course of a 68-year-old patient with TOF who demonstrated a critical increase in right-to-left shunt in a period following AMI. To the best of our knowledge, this is the first adult TOF case reported in the literature that was hemodynamically evaluated both before and after AMI.…”

Section: )mentioning

confidence: 99%

A Critical Increase in Right-to-Left Shunt After Acute Myocardial Infarction in a 68-year-old Male With Tetralogy of Fallot

et al. 2005

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SUMMARYA male patient with tetralogy of Fallot accompanied by aortic regurgitation had maintained sufficient exercise capacity for a number of decades with the status of acyanotic tetralogy of Fallot. When he was 67 years old, he suffered a posterior wall acute myocardial infarction and direct percutaneous coronary angioplasty successfully revascularised the target lesion in the left circumflex artery. However, a few months after the onset of the myocardial infarction, his shortness of breath became clinically significant and was associated with increased right-to-left shunt and increased right ventricular end-diastolic pressure, as well as hypoxia. At 68 years old, therefore, total corrective repair of the tetralogy with replacement of the aortic and pulmonary valves was performed. The patient was asymptomatic after the successful operation. This report suggests that coronary artery disease can be one of the potential factors in inducing critical hemodynamic changes in aging patients with congenital heart disease, especially those who have a shunt between the right and left chambers. The unique clinical course is described with some discussion of the repair of tetralogy in adults. (Int Heart J 2005; 46: 167-174)

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The Clinical Profile and Surgical Treatment of Tetralogy of Fallot in the Adult: Results of Repair in 200 Patients

Cited by 33 publications

References 24 publications

Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up

Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up

Hemoptysis: A 10-Year Retrospective Study

A Critical Increase in Right-to-Left Shunt After Acute Myocardial Infarction in a 68-year-old Male With Tetralogy of Fallot

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