The Clinical Spectrum of Penetrating Injury to the Superior Mesenteric Arterial Circulation

Fullen, William D.; Hunt, John P.; Altemeier, William A.

doi:10.1097/00005373-197208000-00003

Cited by 73 publications

(35 citation statements)

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“…The basic concept underlying the effective use of prophylactic antibiotics to prevent infectious complications in surgical patients is that an adequate amount of an appropriate antibiotic must be present in the tissue before or during a bacterial challenge (1). The concept has been confirmed and accepted in human studies (4,10). Further, this concept probably applies to the therapeutic use of antibiotics which are given to patients perioperatively and after surgical drainage for peritonitis or intra-abdominal abscess.…”

mentioning

confidence: 87%

“…Prophylactic antibiotics are widely used prior to or during elective gastrointestinal surgery, and the importance of the prophylactic antibiotics in reducing postoperative infections has been demonstrated (3,4,10). The aim of a prophylactic administration is to prevent wound infection and peritonitis, both of which may be caused by intraoperative contamination.…”

mentioning

confidence: 99%

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Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery

Doi

Inoue

Hara

et al. 1992

Antimicrob Agents Chemother

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It is not known whether a prophylactic antibiotic administered prior to surgery reaches adequate levels in the peritoneum, where peritonitis may take place. This study determined levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery. Fifteen patients who underwent elective gastrointestinal surgery received an intravenous drip infusion of cefmenoxime (2 g) over 1 h prior to surgery. In patients who underwent gastrectomy, the level of cefmenoxime in serum was 130.8 +/- 6.9 micrograms/ml at laparatomy and decreased to 5.0 +/- 0.7 micrograms/ml at 4 h. Levels in parietal peritoneal and omental tissues at laparotomy were 35.3 +/- 5.2 and 19.2 +/- 3.5 micrograms, respectively, and decreased time dependently. In patients who underwent cholecystectomy, the level of cefmenoxime in serum was 137.9 +/- 7.3 micrograms/ml at laparotomy and decreased to 5.0 +/- 1.2 micrograms/ml at 4 h. Levels in parietal peritoneal and omental tissues were 31.0 +/- 8.4 and 13.7 +/- 3.3 micrograms/g, respectively, and decreased time dependently. The level of cefmenoxime in serum correlated with the levels of cefmenoxime in parietal peritoneum (r = 0.64, P less than 0.01) and in omentum (r = 0.47, P less than 0.02). In patients with appendicitis who received a bolus injection of 2 g of cefmenoxime, the level of drug in inflammatory omental tissue correlated with the level in serum. The levels in peritoneal tissue during surgery lasting up to 2 h were significantly greater than in MIC of cefmenoxime against almost all bacteria reported. A preoperative single dose of 2 g of cefmenoxime probably is effective as a prophylactic for intraoperative contamination.

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mentioning

confidence: 87%

mentioning

confidence: 99%

Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery

Doi

Inoue

Hara

et al. 1992

Antimicrob Agents Chemother

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“…[2325] Fullen and coworkers attempted to classify SMA injuries, and found that at least injuries proximal of the middle colic artery urgently require repair, whereas those of the distal part can be tolerated without ischemia or with ischemia of only a small segment of the bowel. [25] When possible, end-to-end anastomosis of the vessel with or without venous interposition or end-to-side anastomosis to the aorta is the procedure of choice.…”

Section: Aorta and Its Branchesmentioning

confidence: 99%

Anatomical basis for Wilms tumor surgery

2009

J Indian Assoc Pediatr Surg

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Wilms tumor surgery requires meticulous planning and sophisticated surgical technique. Detailed anatomical knowledge can facilitate the uneventful performance of tumor nephrectomy and cannot be replaced by advanced and sophisticated imaging techniques. We can define two main goals for surgery: (1) exact staging as well as (2) safe and complete resection of tumor without spillage. This review aims to review the anatomical basis for Wilms tumor surgery. It focuses on the surgical anatomy of retroperitoneal space, aorta, vena cava and their large branches with lymphatics. Types and management of vascular injuries are discussed.

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“…7,12-36 Ulvestad 38 in 1954 reported the first case of an SMV injury in a patient that sustained an associated SMA injury; the SMV was ligated and the SMA was primarily repaired resulting in patient survival. Fullen,15 in his classical study, describing the anatomic zones and ischemia grades of superior mesenteric artery injuries, described only one patient with an associated SMV injury.…”

Section: Commentsmentioning

confidence: 99%

Superior Mesenteric Venous Injuries: To Ligate or to Repair Remains the Question

Asensio¹,

Petrone²,

García-Núñez³

et al. 2007

Journal of Trauma: Injury, Infection &Amp; Critical Care

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SMV injuries are highly lethal. Multiple associated vessel injuries increase mortality. Mortality correlates well with the American Association for the Surgery of Trauma-Organ Injury Scale for abdominal vascular injuries. Patients undergoing primary repair have higher survival rates (63%) and lesser numbers of associated vascular and nonvascular injuries; whereas those undergoing ligation have a smaller survival rate (40%) and higher number of associated vascular and nonvascular injuries. Ligation appears to be safe and should be selected for hemodynamically unstable patients with a large number of associated injuries.

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The Clinical Spectrum of Penetrating Injury to the Superior Mesenteric Arterial Circulation

Cited by 73 publications

References 0 publications

Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery

Levels of cefmenoxime in sera and peritoneal tissues of patients undergoing gastrointestinal surgery

Anatomical basis for Wilms tumor surgery

Superior Mesenteric Venous Injuries: To Ligate or to Repair Remains the Question

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