The Clinical Study of Gestational Diabetes Mellitus

Khurana, Maxima; Shetty, Meenakshi; Anand, Manan

doi:10.14260/jemds/2015/725

Cited by 1 publication

(1 citation statement)

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“…8 In Khurana M et al study 5.3% of study population had GDM tested by OGTT. 9 American diabetic association (ADA) noticed that 7% of all pregnancies are complicated by GDM. In our study population also GDM prevalance is found to be 7.4%.…”

Section: Discussionmentioning

confidence: 99%

Gestational diabetes mellitus-universal versus selective screening

Hymavathi

Tadisetti

Polisetty

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONDiabetes mellitus is a metabolic disorder characterised by hyperglycaemia resulting from defects in Insulin secretion, action or both. Several distinct types of diabetes mellitus exist and are caused by a complex interaction of genetic, environmental factors and life style choices. 1 The prevalence of diabetes mellitus in India, is found to be 2.4% in rural and 4-11.6% in urban population. High frequencies of impaired glucose tolerance ranging from 3.6-9.1% indicate the potential for further rise in prevalence of diabetes mellitus in the coming decades.2 Normal pregnancy is associated with altered maternal glucose homeostasis and metabolism. It is important to identify a pregnant woman with GDM because of its association with significant metabolic alterations, increased perinatal and maternal morbidity and mortality leading to long term morbidity among the mothers and their off spring. 3 The frequency of GDM and the associated morbidity emphasises the importance of an appropriate screening method. The screening of all pregnant women for GDM universally recommended in the second and third international workshops on GDM and the WHO expert committee on diabetes but the Fourth international workshop conference on GDM including American college of obstetricians and gynaecologists (ACOG) emphasised on selective screening. [4][5][6] Is it possible to use selective screening based ABSTRACT Background:The prevalence of diabetes mellitus is increasing globally and Indian population is found to be ethnically in high risk group. Gestational diabetes mellitus (GDM) offers a unique and valuable opportunity for the development and implementation of clinical strategies for future prevention of diabetes. There is immense need for optimal screening strategies to spot out women with gestational diabetes. Methods: Prospective case study.1000 pregnant women were recruited into the study at an early gestational age (<20 weeks). They were broadly divided into two groups A (without risk factors) and B (with risk factors).The whole study population (both A and B) is subjected to oral glucose challenge test (OGCT) with the concept of Universal screening. Those with abnormal OGCT are subjected to Oral glucose tolerance test (OGTT).Women with abnormal GTT values are designated as having GDM. The results are analyzed. Results: 11.7% in group A and 25.4% in group B were found to have abnormal OGCT values and when they were subjected to OGTT 44.2% in group A and 45.8% in group B are detected to have abnormal OGTT values. 87.9% of GDM women were found to be in the age group 21-25 years in group A and in group B (59.5%) were of >26 years. labor outcome by caesarean section in GDM cases was up to 60% and 51.3% being elective sections. On the whole neonatal outcome was satisfactory. Conclusions: As Indian population are ethnically more prone for diabetes, there is immense need to adopt universal screening for GDM in pregnancy. Thus, a timely action can be taken as depicted in the present study by screening all pregnant women, irrespe...

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Section: Discussionmentioning

confidence: 99%