Posterior reversible encephalopathy syndrome(PRES) is a proposed reversible cliniconeuroradiological entity characterized by headache, altered mental status, cortical blindness, seizures, focal neurological signs and a diagnostic magnetic resonance image showing multiple hyperintense signal in cortical and subcortical white matter. We report a case of 25 year female who presented 2 days postdelivery with posterior reversible encephalopathy syndrome. Early diagnosis with MRI showing bilateral parietal and occipital hyperintensities and treatment with manitol, antiepileptics and supportive measure, the syndrome was fully reversible. Clinicians as well as radiologists should be familiar with this clinically frightening, underdiagnosed condition to assure timely diagnosis and treatment to prevent persistent neurological deficits.
BACKGROUND: Gestational diabetes mellitus (GDM) is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy. It accounts for 90% of the cases of diabetes mellitus in pregnancy. Family history of diabetes and high body mass index are risk factors for developing gestational diabetes mellitus. In high risk populations, the recurrence risk with future pregnancies is also high. AIM AND OBJECTIVE: 1) to study the proportion of GDM among pregnant women between 24 to 28 weeks of gestation. 2) To evaluate and compare the occurrence of GDM in antenatal cases with respect to risk factors e.g.; family history of diabetes, prematurity, history of foetal loss and congenital anomaly. MATERIAL AND METHODS: In this hospital based study, 100gm of oral glucose tolerance test (OGTT) according to Carpenter and Coustan modification of the National Diabetes Data Group was done in women coming for antenatal checkup between 24 to 28 weeks of gestation irrespective of presence or absence of risk factors for GDM. Data was compiled and statistically analyzed. RESULTS: In this study it was observed that 11(5.3%) women developed GDM out of 206 women. All GDM patients have one or more risk factors. Age >25 years (63.6%) fetal loss (36.3%), BMI (33.3%) are common risk factors followed by family history of diabetes (27.3%). CONCLUSION: Family history of diabetes and past history of congenital anomalies are statistically significant in GDM group as compared to non GDM.
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