The Clinical Utility of the Conners’ Continuous Performance Test-II in Traumatic Brain Injury

Zane, Katherine L.; Gfeller, Jeffrey D.; Roskos, P. Tyler; Bucholz, Richard D.

doi:10.1093/arclin/acw078

Cited by 14 publications

(14 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is possible that those subjects with moderate/severe DKA in the Cameron et al ( 9) study may have also had the lower attention scores. Interestingly, adults up to 5 years out from a moderate/severe traumatic brain injury (14) have lower performance on the same CPT2 subtests of Detectability and Commission as did our participants who experienced moderate/ severe DKA. Therefore, deficits in attention may not become detectable until some time after an insult to the developing or mature brain.…”

Section: Discussionsupporting

confidence: 48%

“…In addition, the Conners’ Continuous Performance Test II (CPT2), an assessment of various facets of attention, was administered. During the CPT2, participants are instructed to respond to all letters presented consecutively on a computer screen with a button press, except for a specific target letter (“X”), to which they are instructed to withhold (i.e., inhibit) their response ( 14 ).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Impact of Early Diabetic Ketoacidosis on the Developing Brain

et al. 2018

View full text Add to dashboard Cite

OBJECTIVE This study examined whether a history of diabetic ketoacidosis (DKA) is associated with changes in longitudinal cognitive and brain development in young children with type 1 diabetes. RESEARCH DESIGN AND METHODS Cognitive and brain imaging data were analyzed from 144 children with type 1 diabetes, ages 4 to <10 years, who participated in an observational study of the Diabetes Research in Children Network (DirecNet). Participants were grouped according to history of DKA severity (none/mild or moderate/severe). Each participant had unsedated MRI scans and cognitive testing at baseline and 18 months. RESULTS In 48 of 51 subjects, the DKA event occurred at the time of onset, at an average of 2.9 years before study entry. The moderate/severe DKA group gained more total and regional white and gray matter volume over the observed 18 months compared with the none/mild group. When matched by age at time of enrollment and average HbA 1c during the 18-month interval, participants who had a history of moderate/severe DKA compared with none/mild DKA were observed to have significantly lower Full Scale Intelligence Quotient scores and cognitive performance on the Detectability and Commission subtests of the Conners’ Continuous Performance Test II and the Dot Locations subtest of the Children’s Memory Scale. CONCLUSIONS A single episode of moderate/severe DKA in young children at diagnosis is associated with lower cognitive scores and altered brain growth. Further studies are needed to assess whether earlier diagnosis of type 1 diabetes and prevention of DKA may reduce the long-term effect of ketoacidosis on the developing brain.

show abstract

Section: Discussionsupporting

confidence: 48%

Section: Methodsmentioning

confidence: 99%

Impact of Early Diabetic Ketoacidosis on the Developing Brain

et al. 2018

View full text Add to dashboard Cite

show abstract

“… Daily EF skills using the Brief Daily Survey on self-reported EF skills using ecological momentary assessment [time frame: 30 days between post-intervention assessment and follow-up assessment]. Attentional problems: Performance-based Conners’ Continuous Performance Test 3rd (CPT 3) [ 26 ] [time frame: baseline (at recruitment/before intervention), Post-Intervention (after completion of the intervention, up to 2 weeks), follow-up (up to 6 months after completion of the intervention)]; Self/parent-reported Attention Problem Scale of the Behavioral Assessment System for Children 3rd Edition (BASC-3 APS) [ 27 ] [time frame: follow-up (up to 6 months after completion of the intervention)]. Health-related quality of life using a 23-item PedsQL Generic Core Scales (0–100 after transformation, higher scores indicate better quality of life) [time frame: follow-up (up to 6 months after completion of the intervention)].…”

Section: Interventionsmentioning

confidence: 99%

Efficacy of a virtual reality-based cognitive interactive training program for children with traumatic brain injuries: study protocol for a parallel-group randomized controlled trial

Shen,

Wang,

Quinn

et al. 2024

Trials

View full text Add to dashboard Cite

Background Traumatic brain injury (TBI) is a leading cause of disability in children. Cognitive rehabilitation for this population is critical for their long-term health outcomes. This trial aims to evaluate the efficacy of a virtual reality-based program (VICT) for training executive functions in children with TBI. Methods A parallel group randomized controlled trial will be conducted among up to 32 children with TBI. Children in the intervention group will receive the VICT training while children in the control group will play a comparable VR game without executive function training. Each participant will be assessed at baseline, post-intervention, and 1-month follow-up. Outcomes will include core executive functions, attention, and health-related quality of life measured by computerized tasks or standardized questionnaires. Discussion Cognitive rehabilitation is among the top healthcare needs for pediatric TBI patients. Virtual reality-based training is promising due to its versatile content, flexibility, and potential cost savings for both patients and providers. Findings of this trial will provide data on the efficacy of the VICT program on core executive functions, attention problems, and health-related quality of life and serve as the empirical foundation for future larger multi-site effectiveness trials. Trial registration ClinicalTrials.gov NCT04526639. Registered on August 18, 2020.

show abstract

“…Attention problems, most notably in the sustained domain of attention, are assessed using The Conners Continuous Performance Test-2, utilizing a computer [147][148][149]. The Conners' CPT is a helpful measure in diagnosing ADHD and has been studied on other disorders such as schizophrenia, TBI, and idiopathic epilepsy [147,[150][151][152][153][154][155]. 360 stimuli trials are performed on the screen, in letters presented 1, 2, or 4 s apart (ISI: Inter-Stimulus Interval).…”

Section: The Conners Continuous Performance Test-2mentioning

confidence: 99%

A comprehensive review of attention tests: can we assess what we exactly do not understand?

Nasiri

Khalilzad

Hakimzadeh

et al. 2023

Egypt J Neurol Psychiatry Neurosurg

View full text Add to dashboard Cite

Attention, as it is now defined as a process matching data from the environment to the needs of the organism, is one of the main aspects of human cognitive processes. There are several aspects to attention including tonic alertness (a process of intrinsic arousal that varies by minutes to hours), phasic alertness (a process that causes a quick change in attention as a result of a brief stimulus), selective attention (a process differentiating multiple stimuli), and sustained attention (a process maintaining persistence of response and continuous effort over an extended period). Attention dysfunction is associated with multiple disorders; therefore, there has been much effort in assessing attention and its domains, resulting in a battery of tests evaluating one or several attentional domains; instances of which are the Stroop color-word test, Test of Everyday Attention, Wisconsin Card Sorting Test, and Cambridge Neuropsychological Test Automated Battery. These tests vary in terms of utilities, range of age, and domains. The role of attention in human life and the importance of assessing it merits an inclusive review of the efforts made to assess attention and the resulting tests; Here we highlight all the necessary data regarding neurophysiological tests which assess human attentive function and investigates the evolution of attention tests over time. Also, the ways of assessing the attention in untestable patients who have difficulty in reading or using a computer, along with the lack of ability to comprehend verbal instructions and executive tasks, are discussed. This review can be of help as a platform for designing new studies to researchers who are interested in working on attention and conditions causing deficits in this aspect of body function, by collecting and organizing information on its assessment.

show abstract

The Clinical Utility of the Conners’ Continuous Performance Test-II in Traumatic Brain Injury

Cited by 14 publications

References 40 publications

Impact of Early Diabetic Ketoacidosis on the Developing Brain

Impact of Early Diabetic Ketoacidosis on the Developing Brain

Efficacy of a virtual reality-based cognitive interactive training program for children with traumatic brain injuries: study protocol for a parallel-group randomized controlled trial

A comprehensive review of attention tests: can we assess what we exactly do not understand?

Contact Info

Product

Resources

About