The clinical value of dynamic contrast-enhanced magnetic resonance imaging at 3.0T to detect prostate cancer

Zhang, Xuhui; Quan, Xianyue; Lu, Shi‐Long; Huang, Fanheng; Yang, Jian‐Ming; Chan, Queenie; Lin, Ting

doi:10.1177/0300060514541827

Cited by 6 publications

(4 citation statements)

References 30 publications

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“…Of the 26 studies included in our review, two calculated per-regions and per-patients [ 26 , 29 ]. We identified 21 studies that included DCE combined with other imaging techniques studies of PCa for localization of the tumor (peripheral zone, transition zone and whole gland [ 14 – 34 ], and 7 studies investigated each imaging technique performed per-patients analysis [ 26 , 29 , 35 – 39 ].…”

Section: Resultsmentioning

confidence: 99%

Accuracy of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate cancer: systematic review and meta-analysis

Chen

Zheng

et al. 2017

Oncotarget

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The goals of this meta-analysis were to assess the effectiveness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with prostate carcinoma (PCa) and to explore the risk profiles with the highest benefit. Systematic electronic searched were conducted in database. We used patient-based and biopsy-based pooled weighted estimates of the sensitivity, specificity, and a summary receiver operating characteristic (SROC) curve for assessing the diagnostic performance of DCE. We performed direct and indirect comparisons of DCE and other methods of imaging. A total of 26 articles met the inclusion criteria for the analysis. DCE-MRI pooled sensitivity was 0.53 (95% CI 0.39 to 0.67), with a specificity of 0.88 (95% CI 0.83 to 0.92) on whole gland. The peripheral zone pooled sensitivity was 0.70 (95% CI 0.46 to 0.86), with a specificity of 0.88 (95% CI 0.76 to 0.94). Compared with T2-weighted imaging (T2WI), DCE was statistically superior to T2. In conclusion, DCE had relatively high specificity in detecting PCa but relatively low sensitivity as a complementary functional method. DCE-MRI might help clinicians exclude cases of normal tissue and serve as an adjunct to conventional imaging when seeking to identify tumor foci in patients with PCa.

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Section: Resultsmentioning

confidence: 99%

Accuracy of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate cancer: systematic review and meta-analysis

Chen

Zheng

et al. 2017

Oncotarget

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“…Imaging plays an important role. The spiral CT has improved the sharpness of the image, but there are sometimes artifacts during the CT examination, which interferes with the diagnosis (18). As a commonly used imaging method, MRI images in multiple directions.…”

Section: Discussionmentioning

confidence: 99%

Comparison of diagnostic value of multi‑slice spiral CT and MRI for different pathological stages of prostate cancer

Sui

Zou

et al. 2019

Oncol Lett

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Diagnostic value of magnetic resonance imaging (MRI) and multi-slice spiral CT (MSCT) for different pathological stages of prostate cancer was compared. A total of 112 patients with prostate cancer who underwent surgical pathology in The Affiliated Yantai Yuhuangding Hospital of Qingdao University from February 2014 to January 2016 were enrolled as prostate cancer group, and another 100 patients who received physical health examinations during the same period as the normal group. MSCT and MRI scanning were performed on patients in both groups to analyze their diagnostic value for stages A/B and C/D of prostate cancer. Based on the apparent diffusion coefficient (ADC) value generated by the diffusion-weighted imaging (DWI) in MRI, there was a significant difference in the ADC value between different stages of prostate cancer (P<0.05); the pathological stage was negatively correlated with the ADC value (r=−0.7629, P<0.05), and the higher the stage was, the lower the ADC value was. The sensitivity was significantly higher in the MRI group than that in the MSCT group (92.0 vs. 79.5%, P<0.05), and the specificity was significantly higher in the MRI group than that in the MSCT group (90.0 vs. 70.0%, P<0.05). In the diagnosis of stage A and B of prostate cancer, the diagnostic coincidence rate was 86.7% in the MRI group, and 57.8% in the MSCT group (P<0.05); the misdiagnosis rate and missed diagnosis rate were significantly lower in the MRI group than those in the MSCT group (P<0.05). The accuracy of MRI is higher than that of MSCT in the diagnosis of early prostate cancer. Both MRI and MSCT can accurately detect stages C and D of prostate cancer, but the ADC value in MRI has great clinical significance for judging the risk of the tumor. Therefore, MRI is more valuable than MSCT in the diagnosis of patients with different pathological stages of prostate cancer.

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“…There are several agents approved by the United States Food and Drug Administration, including gadopentetate dimeglumine (Magnevist), gadobutrol (Gadovist), or gadodiamide (Omniscan) [96]. Aiming for a reasonable spatiotemporal resolution, a five-minute DCE acquisition yields dynamic imaging with a temporal resolution in the range of 3-10 s, a spatial resolution in the range of 0.7 9 0.7 mm to 1.9 9 1.9 mm with a slice thickness of 3-4 mm [27,66,91,92,95,[97][98][99][100][101]. Compressed sensing techniques have been implemented into DCE sequences to improve spatiotemporal resolution or increase the coverage.…”

Section: Dynamic Contrast-enhanced Imagingmentioning

confidence: 99%

Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation

et al. 2015

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The use of multiparametric MRI scans for the evaluation of men with prostate cancer has increased dramatically and is likely to continue expanding as new developments come to practice. However, it has not yet gained the same level of acceptance of other imaging tests. Partly, this is because of the use of suboptimal protocols, lack of standardization, and inadequate patient preparation. In this manuscript, we describe several practical aspects of prostate MRI that may facilitate the implementation of new prostate imaging programs or the expansion of existing ones.

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The clinical value of dynamic contrast-enhanced magnetic resonance imaging at 3.0T to detect prostate cancer

Cited by 6 publications

References 30 publications

Accuracy of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate cancer: systematic review and meta-analysis

Accuracy of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate cancer: systematic review and meta-analysis

Comparison of diagnostic value of multi‑slice spiral CT and MRI for different pathological stages of prostate cancer

Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation

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