The Coexistence of Carcinoma and Tuberculosis in the Uterine Cervix: Report of 2 Cases

Abstract

Coexistence of tuberculosis and cancer in the uterine cervix is extremel‐ rare. Two of such cases are presented. In these cases, extension of tuberculous lesions is much wider than cancerous lesions. Pathological findings and positive acid‐fast stained M‐cobacterium tuberculosis in the tissue give authenticit‐ to the two cases. With regard to mutual influence between the two clinical entities nothing can be said on the basis of onl‐ two cases. However, it seems that at least tuberculosis did not aggravate the cancerous lesion.

Female genital system tuberculosis: a retrospective clinicopathological study of 1,548 cases in Turkish women

“…Tumor-TB coexistence is reported mostly as case reports in the literature [25,26]. The differential diagnosis between malignancy and peritoneal TB can be problematic since abdomino-pelvic TB usually masquerades as ovarian cancer.…”

“…Although TB after the Second World War has been almost eradicated in the well-developed countries due to vaccination, early diagnosis, proper antibiotics, and increase in the life standards [8,26], it still seems one of the major problems in the underdeveloped countries and also in the developing countries such as Turkey. Because of immigration, both from one country to another and also to cities, it seems that genital tuberculosis will be reborn in many countries and areas where it is thought to be eradicated [29,30].…”

Coexisting genital malignancies with tuberculosis: A case series with review of literature

“…reported two cases from China in 1985, where both the cases presented with postmenopausal bleeding. [13] Rajaram et al . reported a case of carcinoma cervix with coexisting endometrial tuberculosis in 2004.…”

Coexistent squamous cell carcinoma and tuberculosis in the cervix: a rare case report

“…In 1985, Wu-Hsiung Chen last reported two cases of co-existent carcinoma and tuberculosis of cervix, after that no such case has been reported so far. 5 So, we thought of reporting the present case because of extreme rarity and prognostic significance. On the basis of our experience with this case, it may be difficult sometimes to detect such coexistence in a busy routine histopathological reporting as occasional presence of giant cells in the vicinity of cancer and also other causes of granulomatous cervicitis may give a mistaken diagnosis.…”

“…Last case was reported in 1985. 5 We diagnosed a case of cervical carcinoma with coexistent cervical tuberculosis during our routine histopathological reporting in a 35 year old lady, which seems to merit reporting because of extreme rarity and pathological authenticity.…”