The colorimetric and microfluidic paper-based detection of cysteine and homocysteine using 1,5-diphenylcarbazide-capped silver nanoparticles

Shariati, Sattar; Khayatian, Gholamreza

doi:10.1039/d0ra08615k

Cited by 30 publications

(18 citation statements)

References 40 publications

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“…Since the amino acids examined are relevant in the human body, these sensors were applied to biological fluids such as urine. The good results obtained made the PAD promising for sensing Cys and Hcy in biological samples [139].…”

Section: Pad Sensorsmentioning

confidence: 93%

“…In 2020 Shariati and Khayatian have developed a paper-based analytical device (PAD), able to detect the presence of cysteine (Cys) and homocysteine (Hcy). The sensor is based on the interaction between Ag nanoparticles coated with 1,5-diphenylcarbazide (DPC) and the previously mentioned amino acids [139] (see Figure 10). As seen in the image below, a portion of filter paper is cut out to make a multi-way system for modification.…”

Section: Pad Sensorsmentioning

confidence: 99%

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Gold and Silver Nanoparticle-Based Colorimetric Sensors: New Trends and Applications

et al. 2021

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Gold and Silver nanoparticles (AuNPs and AgNPs) are perfect platforms for developing sensing colorimetric devices thanks to their high surface to volume ratio and distinctive optical properties, particularly sensitive to changes in the surrounding environment. These characteristics ensure high sensitivity in colorimetric devices. Au and Ag nanoparticles can be capped with suitable molecules that can act as specific analyte receptors, so highly selective sensors can be obtained. This review aims to highlight the principal strategies developed during the last decade concerning the preparation of Au and Ag nanoparticle-based colorimetric sensors, with particular attention to environmental and health monitoring applications.

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Section: Pad Sensorsmentioning

confidence: 93%

Section: Pad Sensorsmentioning

confidence: 99%

Gold and Silver Nanoparticle-Based Colorimetric Sensors: New Trends and Applications

et al. 2021

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“…Moreover, white paper offers an excellent background for colorimetric assays. 46,47 With this milieu, to investigate the cyanide ion detection in mPADs, we have developed the patterned microchannel using 3D printing technique (Fig. 8a).…”

Section: Microuidic Paper-based Analytical Devicementioning

confidence: 99%

Rapid colorimetric discrimination of cyanide ions – mechanistic insights and applications

et al. 2022

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“…Since a few years ago, resourceful µPADs have been developed with a variety of detection methods including but not limited to colorimetry [13][14][15], fluorescence [16], chemiluminescence [17], electrochemistry [18,19] and electroluminescence [20]. Among the colorimetric and electrochemical methods, which have found more extensive applications, paper-based electrochemical devices (ePAD), which were firstly published by Dungchai [21], have the advantages of insensitivity to color interferences and fluctuation in the environmental light and are being more quantitative with higher sensitivity and wider linear range compared to colorimetric-based PADs.…”

Section: Introductionmentioning

confidence: 99%

An All-in-One Solid State Thin-Layer Potentiometric Sensor and Biosensor Based on Three-Dimensional Origami Paper Microfluidics

2021

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An origami three-dimensional design of a paper-based potentiometric sensor is described. In its simplest form, this electrochemical paper-based analytical device (ePAD) is made from three small parts of the paper. Paper layers are folded on each other for the integration of a solid contact ion selective electrode (here a carbon-paste composite electrode) and a solid-state pseudo-reference electrode (here writing pencil 6B on the paper), which are in contact with a hydrophilic channel fabricated on the middle part (third part) of the paper. In this case, the pseudo-reference and working electrodes are connected to the two sides of the hydrophilic channel and hence the distance between them is as low as the width of paper. The unmodified carbon paste electrode (UCPE) and modification with the crown ether benzo15-crown-5 (B15C5) represented a very high sensitivity to Cu (II) and Cd2+ ions, respectively. The sensor responded to H2O2 using MnO2-doped carbon paste electrode (CPE). Furthermore, a biosensor was achieved by the addition of glucose oxidase to the MnO2-doped CPE and hence made it selective to glucose with ultra-sensitivity. In addition to very high sensitivity, our device benefits from consuming a very low volume of sample (10.0 µL) and automatic sampling without need for sampling devices.

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The colorimetric and microfluidic paper-based detection of cysteine and homocysteine using 1,5-diphenylcarbazide-capped silver nanoparticles

Abstract: A simple and novel portable method for the quantitative measurement of cysteine and homocysteine in human urine samples is presented.

Cited by 30 publications

References 40 publications

Gold and Silver Nanoparticle-Based Colorimetric Sensors: New Trends and Applications

Gold and Silver Nanoparticle-Based Colorimetric Sensors: New Trends and Applications

Rapid colorimetric discrimination of cyanide ions – mechanistic insights and applications

An All-in-One Solid State Thin-Layer Potentiometric Sensor and Biosensor Based on Three-Dimensional Origami Paper Microfluidics

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