The concept of miasm—evolution and present day perspective

Mathur, Mohit

doi:10.1016/j.homp.2009.05.003

Cited by 5 publications

(3 citation statements)

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“…In modern terms, the concept of 'susceptibility' due to both genetic and environmental factors can be compared with the original concept of 'miasm', as an idea of chronic disorders which make humans vulnerable to diseases. Although the concept of miasm is questionable by scientific pathology, 114,115 Hahnemann seemed to equate miasms to the different ways in which humans can be susceptible to various diseases; as scabies and venereal diseases were widespread in the 19th century, considering them e and their suppression with inappropriate medication of that time e as the source of vulnerabilities for other maladies is obvious. 116 Hahnemann also pioneered the concept of disease prevention when he stated that continuous exposure to noxious environmental influences undermines health (Organon, par.…”

Section: Sensitization and Response To Stressmentioning

confidence: 99%

Cell sensitivity, non-linearity and inverse effects

et al. 2015

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It has been claimed that the homeopathic principle of 'similarity' (or 'similia') and the use of individualized remedies in extremely low doses conflicts with scientific laws, but this opinion can be disputed on the basis of recent scientific advances. Several mechanisms to explain the responsiveness of cells to ultra-low doses and the similarity as inversion of drug effects, have again been suggested in the framework of hormesis and modern paradoxical pharmacology. Low doses or high dilutions of a drug interact only with the enhanced sensitivities of regulatory systems, functioning as minute harmful stimuli to trigger specific compensatory healing reactions. Here we review hypotheses about homeopathic drug action at cellular and molecular levels, and present a new conceptual model of the principle of similarity based on allosteric drug action. While many common drugs act through orthostatic chemical interactions aimed at blocking undesired activities of enzymes or receptors, allosteric interactions are associated with dynamic conformational changes and functional transitions in target proteins, which enhance or inhibit specific cellular actions in normal or disease states. The concept of allostery and the way it controls physiological activities can be broadened to include diluted/dynamized compounds, and may constitute a working hypothesis for the study of molecular mechanisms underlying the inversion of drug effects.

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Section: Sensitization and Response To Stressmentioning

confidence: 99%

Cell sensitivity, non-linearity and inverse effects

et al. 2015

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“…Homoeopathy is known for curing the chronic diseases from the roots and the basic principles on which it is founded have to be really followed for the rational healing and curing [33] . The phenomenon of suppression is a concept fundamental to the Miasm theory because it explains how a single entity, psora, led to multitude of chronic diseases [34] . But these theories and concepts have to be verified and demonstrated on research grounds.…”

Section: Prevention Of Chronic Diseasesmentioning

confidence: 99%

A review on prevention of diseases through homoeopathy

Gilla¹,

Sreelakshmy²

2020

Int. J. Homoeopathic Sci.

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Homoeopathy is one of the latest systems of medicine discovered at the latter part of 18 th century, first rose to prominence in the 19 th century due to its success in treating epidemics and is currently second largely utilized system of medicine globally. Prophylaxis through Homoeopathy has been strongly promulgated by stalwarts and popular among the general public in the recent times, but still controversy revolves around it. Aim of the study is to review the available literature for analyzing the usefulness of Homoeopathy in prophylaxis of human, animal as well as plant diseases. A comprehensive search has been made in electronic database aimed to target the available literature of various levels of evidence. Examples are summarized under different areas of applicability of homeopathic medicine as prophylactic. Currently there is convincing evidence to support effectiveness of Homoeopathy in prophylaxis, though sparse. More rigorous research studies are warranted to enlarge the horizon of its application.

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“…This self-perpetuation of disease, as an organization of pathological attractors in a complex system, can be interpreted as an updating of the "miasm" concept of classic homeopathy. [22][23][24] Modern epigenetics, too, appears to be casting new light on the traditional homeopathic tenets, as for example in the recent findings suggesting the transgenerational transmission of altered brain chemistry and behaviour after a single nonlethal exposure to a fungicide chemical in the original male animal. 25 Such data lend general credence to the homeopathic construct that disease tendencies can be inherited as a result of the stressors and illnesses experienced by the parents and grandparents of the current patient.…”

Section: Blocking Of Communicationmentioning

confidence: 99%

A dynamic network model of the similia principle

Bellavite

Olioso

Marzotto

et al. 2013

Complementary Therapies in Medicine

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The use of drugs in high dilutions and the principle of similarity (or "similia") are two basic tenets of homeopathy. However, the plausibility of both is a subject of debate. Although several models have been proposed to explain the similia principle, it can be best understood and appreciated in the framework of complexity science and dynamic systems theory. This work applies a five-node Boolean network to show how self-organization and adaptation are relevant to rationalizing this traditional medical principle. Simulating the trajectories and attractors of the network system in the energy state-space provides a rudimentary and qualitative illustration of how targeted external perturbations can have pathological effects, leading to permanent, self-sustaining alterations. Similarly, changes that conversely enable the system to find its way back to the original state can induce therapeutic effects, by causing specific shifts in attractors when suitable conditions are satisfied. Extrapolating these mechanisms to homeopathy, we can envisage how major changes in the evolution of homeodynamic systems (and, eventually, healing of the entire body) can be achieved through carefully selected remedies that reproduce the whole symptom pattern of the ill state.

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The concept of miasm—evolution and present day perspective

Abstract: This paper reviews the circumstances in which the concept of miasm evolved and how subsequent developments in medicine have improved our understanding of the cause of diseases. It concludes with an emphasis on the need to further refine the homeopathic concept of disease.

Cited by 5 publications

References 4 publications

Cell sensitivity, non-linearity and inverse effects

Cell sensitivity, non-linearity and inverse effects

A review on prevention of diseases through homoeopathy

A dynamic network model of the similia principle

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