The conception of the reticular organization of the nervous tissue of Alexander Dogiel

Os, Sotnikov; Markov, Igor

doi:10.20340/mv-mn.18(26).01.8-19

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…The first group of retrograde signals includes substances that freely penetrate the postsynaptic membrane. The second group includes substances that are secreted from the postsynaptic membrane by secretion [12]. Thus, on the set in the work by O.S.…”

Section: Fig 1 Broad-mesh Network Between Protoplasmic Processes Of Nerve Cells 1 -Dogel's Cell Of the 2 Nd Type In The Frontal Plane 2 -mentioning

confidence: 99%

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Neuron Structure of the Ganglion Plexuses in the Large Intestine

Babayeva¹

2021

ArveMED

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Aim of the study: The aim of the work: to study the syncytial connections in the ganglia of the nerve plexuses of the large intestine. Material and research methods: The work was carried out on 30 sexually mature Wistar rats at the age of 3–4 months, having a mass of 180–320 g by the beginning of the experiment. The study used a universal method of impregnation, based on classical impregnation methods: intravascular — Rannier–Goyer and immersion — Bilshovsky–Gros. The study was conducted in 2019–2020. Results: According to our data, the large intestine has intraorgan ganglia located in the intermuscular and submucosal plexuses. The intermuscular plexus (Auerbach) of the large intestine has the form of a network with cells of various shapes and consists of nerve nodes containing cells of types I and II of Dogiel, however, the latter are numerically significantly predominant (20–25 cells or more). Syncytial connections of neurons in the autonomic ganglia of the intestine were constantly detected. These were syncytial connections of processes and bodies of two neurocytes. Protoplasmic processes of nerve cells diverge in different directions, go to meet similar branches, joining them, form a narrow or wide-looped network. Syncytial connections between the bodies of neurons and peripheral processes form closed annular anastomoses. Interfiber cytoplasmic bonds are formed by membrane syncytial fusion. Conclusion. The large intestine has intraorgan ganglia located in the intermuscular and submucosal plexuses. Syncytial connections of neurons in the autonomic ganglia of the intestine were constantly detected. Interfiber cytoplasmic bonds are formed by membrane syncytial fusion.

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Section: Fig 1 Broad-mesh Network Between Protoplasmic Processes Of Nerve Cells 1 -Dogel's Cell Of the 2 Nd Type In The Frontal Plane 2 -mentioning

confidence: 99%

“…Obviously, instead of the current representation of either -or or synapses, or epaps, it is necessary to represent and -and, i.e. and synapses and epaps [12].…”

Section: Fig 1 Broad-mesh Network Between Protoplasmic Processes Of Nerve Cells 1 -Dogel's Cell Of the 2 Nd Type In The Frontal Plane 2 -mentioning

confidence: 99%

Neuron Structure of the Ganglion Plexuses in the Large Intestine

Babayeva¹

2021

ArveMED

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Neuronal Syncytia in the Enteric Nervous System of the Felis Catus

Markov

Markova

et al. 2022

MorphoLetter

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Syncytial connections between neurites were found using electron microscopy in the nervous system of cats, young pigs, as well as in the culture of mollusk ganglia cells. The possibility of detecting neural syncytia using the method of the unmasking of digital images of arborizations of interneuronal connections in the nervous tissue of the brain was established, but this method was not used to study of the enteric nervous system. The aim of the study was to analyze the submucosal and intermuscular autonomic nerve plexuses of the intestine of the domestic cat (Felis catus) by method of the unmasking of digital images. The material for the study was preparations of the small and large intestines. All manipulations with animals were carried out in compliance with Directive 2010/63/EU of the European Parliament and of the Council of the European Union on the protection of animals used for scientific aims. The experiments were carried out on mature outbred cats (n=45). To obtain preparations, the intestinal vessels of experimental animals were sequentially perfused with solutions of barium hydroxide, then silver nitrate, and hydroquinone. After perfusion, intestinal preparations were taken and fixed. The obtained histological preparations (including ultramicroscopic ones) were studied by the method of unmasking of digital images (of the downscaling of the image resolution). As a result of the study, numerous distant syncytial anastomoses connecting the bodies of neurocytes of all types of Dogiel cells were revealed for the first time, and their properties were established. Widespread multiple morphological mono- and polyvalent ring syncytial structures were found. Their supposed function is the opposite direction of electric and axoplasmic flow. An in vivo feature of the reflex syncytial apparatus of the enteric nervous system is the formation of multi-tiered closed loop-like contacts of nerve fibers and type II Dogiel cells with pronounced local and diffuse receptor branches. Thus, a characteristic feature of the enteric nervous system is the presence of multicellular connections of neurocytes in the form of a network of distant syncytial anastomoses. These anastomoses are real proof of the reticular principle of the structural organization of the autonomic plexuses of the enteric nervous system and the reticular concept in general.

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Regulation of the vital activity of cells, tissues and organs in the human body and mechanisms for its implementation (review)

Milyukov

Sharifova

Nguen

2022

Regional blood circulation and microcirculation

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The unity of the organism and the ambient environment is realized by the nervous system and the humoral regulation. Based on this, all the variety of mechanisms for the functional activity regulation of the human body, experts traditionally classify into nervous and humoral processes, indicating that they are practically inseparable and constitute a united system. The advantages of one system compensate for possible shortcomings of the other, however, the vulnerability of the neuro-reflex mechanism of regulation is extremely high, and the state of knowledge of nervous regulation is higher, since it is amenable to registration by instrumental devices. At the same time, it is obvious that humoral regulation is one of the evolutionarily earliest mechanisms for regulating vital processes and, therefore, the most tested in practical use and, due to the preservation of this method of regulating homeostasis in the body, the most reliable and evolutionarily proven, but the study of humoral mechanisms regulation of the functions on the cellular and organ level is complicated by the vastness of subordinate tissues. Further painstaking research work is needed to study both the possibilities of humoral regulation in the human body and further study of the hemocirculatory system reactivity. This work can be the most important factor in the development of evidence-based medicine, validation of treatment policy for various pathological processes, objectification of control and estimated results of treatment.

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The conception of the reticular organization of the nervous tissue of Alexander Dogiel

Cited by 4 publications

References 21 publications

Neuron Structure of the Ganglion Plexuses in the Large Intestine

Neuron Structure of the Ganglion Plexuses in the Large Intestine

Neuronal Syncytia in the Enteric Nervous System of the Felis Catus

Regulation of the vital activity of cells, tissues and organs in the human body and mechanisms for its implementation (review)

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