The Condensation of Alcohols, Ethers, and Esters with Aromatic Hydrocarbons in the Presence of Aluminum Chloride

Norris, James F.; Sturgis, B. M.

doi:10.1021/ja01875a027

Cited by 47 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While boron fluoride forms dialcoholates which, in the case of primary alcohols, are stable enough to be distilled (30), both boron and aluminum chlorides are vigorously decomposed by alcohols. In fact, the latter reaction has been recommended for the preparation of methyl, ethyl, and propyl chlorides (37).…”

Section: \Zmentioning

confidence: 99%

Substitution and Orientation in the Benzene Ring.

Price¹

1941

Chem. Rev.

View full text Add to dashboard Cite

Section: \Zmentioning

confidence: 99%

Substitution and Orientation in the Benzene Ring.

Price¹

1941

Chem. Rev.

View full text Add to dashboard Cite

“…In this reaction an alkyl group will be added to the aromatic compound in the presence of a catalyst and new C-C bond is formed [15][16][17] . Common methods of Friedel -Crafts alkylation are: a) alkylation using alkyl halide in the presence of Lewis acid, b) alkylation using an alkene in the present of Lewis acid, c) alkylation using an alcohol in the present of lewis acid 21 . The mechanism of electrophilic substitution reaction begins with the formation of carbocation (I) and then an aromatic compound attack to carbocation as a nucleophile and arenium ion is formed, arenium ion with the loss of a proton is changed to benzene alkyl 21 .…”

Section: Introductionmentioning

confidence: 99%

Investigation of Friedel‐Crafts Alkylation in the Presence of Supported Sulfonic Acid on Silica Gel

Kiasat

Karimi-Cheshmeali

Soleymani

et al. 2011

Journal of Chemistry

View full text Add to dashboard Cite

From the Reaction between cellulose and chloro sulfonic acid was prepared sulfuric acid cellulose composition as a new solid acid. The solid acid supported on silica gel and then as an effective catalyst in Friedel-Crafts alkylation of alcohols and aromatic compounds was used. The reaction progress was controlled using thin layer chromatography and the reaction products were analyzed using IR spectroscopy devise. The results show this new catalyst is effective in the friedel crafts alkylation and C-C bond formation was done in short time with very good yields.

show abstract

“…of MeLi in EtzO with a low LiCl content was prepared from CH3C1 by reaction with 6Li powder as described in [29]. For the deuterated sample, CD3Cl was synthezised from CD,OD and AICl, [30]. The MeLi concentrations were determined by the Gilman procedure [31].…”

Section: Relative To 0 I M Libr In T H Fmentioning

confidence: 99%

ChemInform Abstract: NMR Spectroscopy of Organolithium Compounds. Part 11. 2H/1H Isotope Shifts for 6Li‐NMR: First Experimental Detection and Applications to Structural Problems in the Field of Organolithium Compounds

Eppers

Guenther

1991

ChemInform

View full text Add to dashboard Cite

Dedicated L o Professor P. von Ruguc' Schleyer on the occasion of his 60th birthday (30.VII.90) Deuterium-induced isotope effects on 'Li chemical shifts, transmitted over two bonds, * A (6Li)(2H/'H), have been measured for the first time for methyllithium and the system methyllithium/lithium iodide. The observed shifts are to low field and range from 15 to 20 ppb per CD, group. The multiplicity and intensity distribution of the 'Li signals resulting for mixtures of CH3-and CD3-containing samples in the limit of slow inter-as well as intru-aggregate exchange yield information about the size of the various clusters present in diethylether solution. It is expected that these isotope shifts can facilitate structural investigations of organolithium compounds. In some cases, the results of such measurements are expected to be less ambiguous then the conclusions based on multiplets that arise from scalar 13C,6Li spin-spin coupling.

show abstract

The Condensation of Alcohols, Ethers, and Esters with Aromatic Hydrocarbons in the Presence of Aluminum Chloride

Cited by 47 publications

References 0 publications

Substitution and Orientation in the Benzene Ring.

Substitution and Orientation in the Benzene Ring.

Investigation of Friedel‐Crafts Alkylation in the Presence of Supported Sulfonic Acid on Silica Gel

ChemInform Abstract: NMR Spectroscopy of Organolithium Compounds. Part 11. 2H/1H Isotope Shifts for 6Li‐NMR: First Experimental Detection and Applications to Structural Problems in the Field of Organolithium Compounds

Contact Info

Product

Resources

About