“…Thus, although the influence of heterogeneous and anisotropic tissue on the electric field was generally in the sub-millimetre level there were cases where the electric field diameter was altered by up to 1.2 mm at the inner isolevel (Table 4). and Kay [33] are measured in tissue samples at frequencies way beyond standard DBS frequencies. Other factors that may influence measurements performed in vivo is the tissue temperature, bleeding, leakage of CSF, decreased blood-flow due to anaesthetic agents, or increased pressure caused by the probe [34].…”