The constituents of cacalia decomposita a. gray. structures of maturin, maturinin, maturone and maturinone

Modified eremophilanes and anti-inflammatory activity of Psacalium cirsiifolium

“…The antimicrobial effects of P. radulifolium 10 and the antiinflammatory properties of P. sinuatum 11 have also been determined. Sesquitepenes mainly of eremophilane and modified eremophilane types are the main secondary metabolites isolated from the eight species of the genus chemically studied so far: P. decompositum [4][5][6] (also studied as Cacalia decomposita), 12,13 P. tussilaginoides (studied as Cacalia ampulacea), 13 P. peltatum, 7,8 P. sinuatum,…”

“…17,18 As continuation of our research on Senecioneae we studied the chemical composition of P. cirsiifolium which to the best of our knowledge has no previous studies. We report the isolation of fourteen modified eremophilane derivatives (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14), of which four (1-4) are described for the first time. Two known caryophyllenes (16,18), one aromadendrene (17) and one flavonoid (15) were also isolated ( Figure 1).…”

Three new and two rare furanoeremophilanes from senecio asirensis

“…The other compounds were also characterized by spectral studies and compared with the reported values, whereupon compound 4 was identified as 9-methoxyl-4,11-dimethylnaphtho [2,3-b ]furan, named as 14-nordehydrocalohastine, which has been reported previously from Senecio linifolius [6], whereas compound 5, 4,11-dimethylnaphtho[2,3-b ]furan-6,9-dione (designated as maturinone), has been isolated previously from Cacalia decomposita [7].…”

“…We have isolated three new furanoeremophilanes from the aerial parts of the plant, which have been characterized as 6-hydroxylmethyl-9-methoxyl-4,11-dimethylnaphtho [2,3-b ]furan, designated as asirensane-a (1), 6-hydroxyl-1,2-dimethoxyl-4,6,11-trimethyl-6-hydronaphtho[2, 3-a ]furan-7-one, named asirensane-b (2), and (6,12-dihydroxyl-9-methoxyl-4-methyl-11-acetyl-3,4-dihydronaphtho [2,3-b ]furan-3-yl)methyl (2 0 Z)-2 0 -methylbut-2 0 -enoate, designated asirensane-c (3). Two rare furanoeremophilanes were also isolated and characterized from this source, namely 9-methoxyl-4,11-dimethylnaphtho [2,3-b ]furan, named 14-nordehydrocalohastine (4, earlier reported also from Senecio linifolius [6]), and 4,11-dimethylnaphtho [2,3-b ]furan-6,9-dione designated maturinone (5, previously isolated also from Cacalia decomposita [7]). The genus Senecio is mainly reported to possess eremophilanolides/eudesmanolides that contain an unsaturated cyclic system, and an a,blactone in the furan ring [8], whereas the compounds obtained from Senecio asirensis possess a saturated cyclic ring system without an a,b-lactone ring in the furan ring, which are less common among reported eremophilanolides.…”

Crystal Structure of Maturin acetate from <i>Psacalium peltatum</i> (Kunth) (<i>matarique</i>)

“…Hexane extract of roots from P. peltatum, was separated in a column chromatographic process and elueted with hexane-ethyl acetate in a mixture gradient, from fraction (98:2) elueted of hexane-ethyl acetate was isolated Maturin acetate and their spectroscopic features were compare with the described data. 5,6 A yellow crystal prism was mounted on a glass fibber. The X-ray intensity data were measured at 298 K on a Bruker Smart Apex diffractometter with a CCD area detector system equipped with Mo Ka radiation (l = 0.71073 Å).…”