The contribution of hysteroscopy to the detection malignancy in symptomatic postmenopausal women

Abstract

Hysteroscopic evaluation of endometrial cavity is widely used in cases of abnormal uterine bleeding. The aim of the present study is to compare the hysteroscopic and histological findings in women suffering from postmenopausal bleeding. Between 1990 and 2009, 425 women aged 47-83 years were included in the study. None of the women had received hormonal therapy or had any malignancy in the past. All women underwent diagnostic hysteroscopy and histologic sampling of the endometrial cavity. Hysteroscopy was successfully completed in 423 women and was suggestive of malignant lesions in 23 cases, which were confirmed histologically. The hysteroscopic findings in three cases were suggestive of atrophic endometrium, atypical hyperplasia and endometrial carcinoma, and the histologic diagnosis confirmed endometrial carcinoma (two cases) and one uterine sarcoma. Hysteroscopy proves to be a safe and effective technique in the diagnosis and management of abnormal uterine bleeding.

Reproducibility of Endometrial Pathologic Findings Obtained on Hysteroscopy, Transvaginal Sonography, and Gel Infusion Sonography in Women With Postmenopausal Bleeding

“…TVS and GIS have varying efficiencies with regard to making a diagnosis of endometrial hyperplasia [50,51] because this diagnosis relies on a nonspecific thickening of the endometrium. The difficulties involved in using HY to differentiate between hyperplasia and other abnormalities have previously been described [52][53][54] and are even noted by experienced hysteroscopists [45,55].…”

Endometrial Sampling Methods: A Case Report and Literature Review

“…In Liberis et al study, specificity, sensitivity and positive predictive values of hysteroscopy to distinguish endometrial benign pathology such as cervical polyps, endometrial fibroma were 100% and specificity, sensitivity and positive predictive values were 88.9%, 42.3%, 94.3% in cases with atrophic endometrium, respectively. 27 Additionally, hysteroscopy had a specificity of 91.3%, a sensitivity of 91.3% and positive predictive values of 99.5% for the detection of endometrial malignancy in their study. 27 In another study rewieving the hysteroscopic reports of 25 menopausal patients treated by hysterectomy, the correlation was found between the pathologic findings on the uterine specimen and the diagnoses obtained by hysteroscopic view.…”

“…27 Additionally, hysteroscopy had a specificity of 91.3%, a sensitivity of 91.3% and positive predictive values of 99.5% for the detection of endometrial malignancy in their study. 27 In another study rewieving the hysteroscopic reports of 25 menopausal patients treated by hysterectomy, the correlation was found between the pathologic findings on the uterine specimen and the diagnoses obtained by hysteroscopic view. 28 Also, sensitivity, specificity, and negative and positive predictive values of hysteroscopy to foresee a diagnosis of infiltrating carcinoma were 84.6%, 100%, 87.5%, and 100%, respectively in patients with a diagnosis of atypical hyperplasia on endometrial biopsy.…”

Ultrasound Measurement of Endometrial Thickness for Detecting Endometrial Malignancy

“…Widespread utilize of sonography comprises too allow able accompanying ET result into asymptomatic post-menopausal females. Though, it devises been optional that the 4-mm or 5-mm confines usually utilized to exclude Malignancy into symptomatic post-menopausal females are not transportable to asymptomatic patient 13,14 . So, our aim was for assessing analytic value of sonography, slow ET in forecasting - ---------------------------------------------------------------------------------------Received on 11-01-2021 Accepted on 17-05-2021 Endometrial Pathologies within post-menopausal females among Vaginal Bleeding as well as in those by asymptomatic thickened endometrium (≥5 mm).…”