Quality management system (QMS) and knowledge management system (KMS) are two management discipline that are widely used in organizations. The implementation and adoption of QMS is a continuous effort that helps organizations to improve their quality and performance. If adoption of QMS to improve organization's quality, the purpose of KMS implementation in organization on the other hand as a platform and tools to support the management of knowledge activities. In view of the massive activities of knowledge creation, knowledge sharing and repository of knowledge within higher education institution (HEI), the use of KMS will provide greater benefits to stakeholders within HEIs. Past studies have shown that both management disciplines (QMS and KMS) have positive impact towards organizations in term of costs reduction, work performance and business continuity. HEI are also facing with challenges and obstacles because of the growing demand like any other organization. Some of the major challenges faced by HEI such as rising costs of tuition fees, growing number of competition among colleges and universities and introduction of new learning methods and technologies. The purpose of this study is to conceptually explore and identify the needs and potential integration between QMS and KMS within HEI. Based on the discussion and findings, this research provides future direction for more research on two-management disciplines.