This paper proposes a novel analytical approach to analyse the queuing delay and medium access distribution of CSMA-CA protocols over Multihop Personal Area Networks (MPANs). The proposed approach considers a general case without restrictions on the topology, traffic generation patterns or multipath routing policy and accounts for heterogeneous traffic patterns, all possible packet loss scenarios and the effect of the length of the back-off on the channel assessment. This work uses statistical theorems to derive the Moment Generating Function (MGF) of the time required to service a packet, then uses this function as a service distribution in a GI/G/1 queuing model to derive the inter-departure and total queuing delays. From these functions the end-to-end delay, jitter, throughput and failure transmission probability over a path are derived. Besides determination of these metrics, this study exploits the statistical features of the MGF to determine the rare event probability of the service function. The proposed approach is exemplified using the state-of-the-art IEEE 802.15.4 CSMA-CA protocol, and its accuracy is demonstrated through comparison with simulations.Index Terms-Queuing delay, medium access control, multihop, CSMA-CA, IEEE 802.15.4. 0018-9545 (c)