The COVID 19-AN OVERVIEW ON EPIDEMIOLOGY, SYMPTOMS, PREVENTION, MANAGEMENT, TREATMENT AND ROLE OF HEALTH WORKERS

Abstract

With the first case of a highly infectious virus named Coronavirus in Wuhan, China in December 2019, this deadly virus was declared a pandemic by WHO. COVID-19 was found to be very similar to patients infected with MERS-CoV and SARS-CoV. The virus was transmitted from bats to humans through some unidentified intermediary. Since its introduction in humans, it has infected 118000 people, killing 3583 till last week of May 2020 in India. The reported route of transmission is inhalation or direct contact with the infected surface or patients. This symptomatic disease includes symptoms such as cough, fever, sore throat, fatigue, and in some severe patients, it may cause multiple organ failure, pneumonia, severe or acute respiratory diseases. In some cases people may be asymptomatic till 14 d of infection. The patients with mild illness are usually isolated and others are prevented with protective measures such as medical mask, hand hygiene. In the present article, the epidemiology, route of transmission, clinical symptoms, prevention, management, treatment and role and responsibility of health workers is overviewed on the basis of published research and review articles and current state of knowledge.

Detailed View on Repurposed Drugs, Tracking of Vaccines,and Brief View on Prophylactic Nanomedicines as an Alternative Approach and Patient Care for Covid-19

“…Transmission can occur by direct contact with an infected person or by indirect contact with the infected person's environment and substances [12]. Air bone spread is different from that of droplet spread as it refers to microbes in the droplet nuclei that can remain in the air for an extended time and can transmit within a distance of 1meter [13].…”

Assessment of the Possible Causes of Diabetes Mellitus Developed in Patients Post Covid-19 Treatment in a Tertiary Care Hospital

“…Such cases have been seen in India. Still, less acknowledged and known about as well as less studied [14]. Quantifiable data regarding the same can be obtained from the United Kingdom, the United States of America, and other first-world countries [15].…”

Molecular Docking Study Between 3 Thai Medicinal Plants Compounds and Covid-19 Therapeutic Protein Targets: Sars-Cov-2 Main Protease, Ace-2, and Pak-1

“…Until now, there is no FDA-approved or specific treatment for COVID-19 infection. Clinical guidance of the World Health Organization (WHO) and Centers for Disease and Control Prevention (CDC) only include prompt supportive care like oxygen therapy, fluid management, empiric antimicrobials (in case of sepsis), and others [1,4]. Investigational agents reported some potential therapy for COVID-19 such as remdesivir or chloroquinone and combined protease inhibitor lopinavir-ritonavir, which are previously used to treat against SARS and MERS-CoV but their efficacy is still unclear and needs further evaluation [5][6][7].…”