The cranial meninges: Anatomic considerations

Woldenberg, Rona; Lane, Elizabeth; Cinnamon, Jay; Farmer, Peter; Hyman, Roger A.

doi:10.1016/s0887-2171(05)80017-4

Cited by 38 publications

(25 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The meningeal layer (dura mater proper) is firmly attached to the endosteal layer except at the sites of the venous sinuses and the sites of dural reflections (Fig. 3) [20,50,56,68]. It communicates with the dura of the spinal cord at the level of the foramen magnum.…”

Section: Anatomymentioning

confidence: 99%

“…They divide the cranial cavity into wellsupported, freely communicable subdivisions [20,68]. The largest of these septa is the falx cerebri (Figs.…”

Section: Dural Reflectionsmentioning

confidence: 99%

“…3, 4 and 5), which is a sickle-shaped, midline reflection that extends vertically between the two cerebral hemispheres. It extends from the internal frontal crest and crista galli anteriorly, to the internal occipital protuberance and the superior surface of tentorium cerebelli posteriorly [20,68,70]. Ossification dural reflections, mainly of the falx cerebri, albeit rare, have been reported in literature.…”

Section: Dural Reflectionsmentioning

confidence: 99%

“…The U-shaped free margin is called the tentorial notch (incisura tentoria), through which the midbrain passes. The fixed margin adheres to the clinoid processes, the superior borders of the petrous part of temporal bone laterally, and the margins of the transverse sinuses grooves on the occipital bone posteriorly [10,20,68]. At the apex of the petrous bone, and below the superior petrosal sinus, the lower layer of the tentorium pouch anteriorly to form a recess for the trigeminal nerve and ganglion [68].…”

Section: Dural Reflectionsmentioning

confidence: 99%

See 3 more Smart Citations

The cranial dura mater: a review of its history, embryology, and anatomy

et al. 2012

View full text Add to dashboard Cite

show abstract

Section: Anatomymentioning

confidence: 99%

“…They divide the cranial cavity into wellsupported, freely communicable subdivisions [20,68]. The largest of these septa is the falx cerebri (Figs.…”

Section: Dural Reflectionsmentioning

confidence: 99%

Section: Dural Reflectionsmentioning

confidence: 99%

Section: Dural Reflectionsmentioning

confidence: 99%

See 2 more Smart Citations

The cranial dura mater: a review of its history, embryology, and anatomy

et al. 2012

View full text Add to dashboard Cite

show abstract

“…This does not mean that it must represent the subdural space, which is being widely discussed in the scientific medium. For Zaki 17 , Schachenmayr & Fried 26 and Greenberg et al 27 , this space is not observed under normal conditions.…”

Section: Fig 6 Photomicrograph Evidencing Of the Outer Surface Of Thmentioning

confidence: 90%

Tridimensional architecture of the collagen element in the arachnoid granulations in humans: a study on scanning electron microscopy

Conegero

Chopard

2003

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

The arachnoid granulations of adult individual of both sexes were studied through scanning electron microscopy. The dura mater and arachnoid meninges of individuals were collected at the Service of Death Verification of São Paulo - USP and fixed in Karnovsky solution. After this period the material was prepared for analysis in electron microscope. Our results demonstrated that the arachnoid granulations are formed by a pedicle, body and apex, being surrounded by a capsule of connective tissue, which in turn is composed of, basically, bundles of collagen fibers that line pores of different shapes and sizes. The smaller pores are lined by tiny bundles and are located at the apical region of the granulation and the larger are lined by thicker bundles and are located at the lateral regions. In the body we verified that the bundles of collagen fibers compose a fibrous meshwork and in some regions these bundles have circular orientation, forming pores similar to those found at the region of the capsule.

show abstract

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination

Hecht

Siegenthaler

Patterson

et al. 2010

Annals of Neurology

View full text Add to dashboard Cite

Objective Cortical malformations are important causes of neurological morbidity, but in many cases their etiology is poorly understood. Mice with Foxc1 mutations have cellular defects in meningeal development. We use hypomorphic and null alleles of Foxc1 to study the effect of meningeal defects on neocortical organization. Methods Embryos with loss of Foxc1 activity were generated using the hypomorphic Foxc1hith allele and the null Foxc1lacZ allele. Immunohistologic analysis was used to assess cerebral basement membrane integrity, marginal zone heterotopia formation, neuronal overmigration, meningeal defects, and changes in basement membrane composition. Dysplasia severity was quantified using two measures. Results Cortical dysplasia resembling cobblestone cortex, with basement membrane breakdown and lamination defects, is seen in Foxc1 mutants. As Foxc1 activity was reduced, abnormalities in basement membrane integrity, heterotopia formation, neuronal overmigration, and meningeal development appeared earlier in gestation and were more severe. Surprisingly, the basement membrane appeared intact at early stages of development in the face of severe deficits in meningeal development. Prominent defects in basement membrane integrity appeared as development proceeded. Molecular analysis of basement membrane laminin subunits demonstrated that loss of the meninges led to changes in basement membrane composition. Interpretation Cortical dysplasia can be caused by cellular defects in the meninges. The meninges are not required for basement membrane establishment but are needed for remodeling as the brain expands. Specific changes in basement membrane composition may contribute to subsequent breakdown. Our study raises the possibility that primary meningeal defects may cortical dysplasia in some cases.

show abstract

The cranial meninges: Anatomic considerations

Cited by 38 publications

References 37 publications

The cranial dura mater: a review of its history, embryology, and anatomy

The cranial dura mater: a review of its history, embryology, and anatomy

Tridimensional architecture of the collagen element in the arachnoid granulations in humans: a study on scanning electron microscopy

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination

Contact Info

Product

Resources

About