The Current Diagnosis of Superficial Bladder Cancer Must Be Reconsidered

Zaak, Dirk; Hofstetter, A.

doi:10.1159/000065552

Cited by 7 publications

(6 citation statements)

References 43 publications

(37 reference statements)

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“…(Fradet et al, 2007) Zaak et al showed similar results of a CIS detection rate of 91.2% for BLC and 47.2% for WLC. (Zaak and Hofstetter, 2002) Likewise, our study showed that 89.9% (17/19) of CIS lesions were detected by BLC.…”

Section: Discussionsupporting

confidence: 68%

“…Sensitivity and specificity of WLC and PDD are 46%-80% and 76-97%, and 43%-98% and 35-66%, respectively. (Zaak and Hofstetter, 2002;Grimbergen et al, 2003;Jichlinski et al, 2003;Schmidbauer et al, 2004;Fradet et al, 2007;Grossman et al, 2007;Jocham et al, 2008;Stenzl et al, 2008;Geavlete et al, 2012) Now PDD is emerging to diagnose NMIBC or carcinoma in situ. However no studies specifically used PDD for muscle invasive bladder cancer, cystoscopic observation for BCG failure cases or 2nd-TUR cases.…”

Section: Introductionmentioning

confidence: 99%

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Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR

Takai¹,

Inamoto²,

Komura³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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Background: Despite widely adopted standard methods for follow-up including cystoscopy plus cytology, recurrence rates of non muscle-invasive bladder cancer (NMIBC) have not improved over the past decades, still ranging from 60% through 70%. Hence, widely acceptable surveillance strategies with excellent sensitivity are needed. Early recurrence has led to the development of a novel cystoscopy technique utilizing photodynamic diagnosis (

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Section: Discussionsupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR

Takai¹,

Inamoto²,

Komura³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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“…However, a significant proportion of patients with superficial bladder cancer are at risk for recurrence and progression. The risk factors for tumor recurrence and/or progression may be summarized as follows: i) New tumor occurrence and progression; ii) tumor implantation during transurethral resection (TUR); iii) residual tumor following incomplete resection and/or iv) overlooking of neoplastic lesions such as dysplasia and carcinoma in situ (CIS) (25). Tumor recurrence and/or progression are partially attributed to the detection tools.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of optical coherence tomography in bladder cancer patients: A systematic review and meta-analysis

Huang

Zhang

et al. 2018

mol clin onc

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Abstract.A meta-analysis was performed to evaluate the accuracy of optical coherence tomography (OCT) for diagnostic accuracy studies in bladder cancer patients. English language studies reporting the diagnostic accuracy of OCT for bladder cancer were retrieved from the PubMed, EMBASE and Cochrane Library databases in December 2014. Histopathology was a reference standard. Sensitivities, specificities, positive likelihood ratios and negative likelihood ratios were calculated, and summary receiver operating characteristic curves were drawn to determine the diagnostic accuracy of OCT. Finally, 9 eligible studies (468 patients) were included in our meta-analysis. The pooled sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of OCT were 0.96 [95% confidence interval (CI): 0.94-0.98], 0.82 (95% CI: 0.80-0.85), 6.83 (95% CI: 3.24-14.1) and 0.05 (95% CI: 0.02-0.16), respectively. The summary diagnostic odds ratio was 138.88 (95% CI: 29.63-650.89) and the overall area under the curve was 0.9735. These results suggest that OCT has excellent diagnostic performance in patients with bladder cancer and recurrent lesions.

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“…The fluence rate was measured using a power meter (LaserCheck, Coherent). PDT treatment was designed to study the effect of increasing light doses: 1 J/cm 2 …”

Section: Photodynamic Therapy In Cam Modelmentioning

confidence: 99%

“…Fluorescence diagnosis is based on the accumulation of the photosensitizer in malignant tissue that emits fluorescence in the red region of the visible spectrum under blue-light excitation. It is now emerging as a promising tool for the early detection of small or poorly differentiated neoplastic changes [2]. Studies have shown that the therapeutic outcome of topical photosensitizers is in part influenced by pharmaceutical and physicochemical considerations, such as tissue-penetration characteristics and the delivery of the photosensitizing agent into the cancer cells [3].…”

Section: Introductionmentioning

confidence: 99%

Membrane transport enhancement of chlorin e6‐polyvinylpyrrolidone and its photodynamic efficacy on the chick chorioallantoic model

Chin

Heng

Lim

et al. 2008

Journal of Biophotonics

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We have determined the influences of polyvinylpyrrolidone (PVP) on the topical delivery of chlorin e6 (Ce6) in malignant bladder cells. The chick chorioallantoic membrane (CAM) was used to model the tumor spheroids that resemble small residual bladder tumors prior to vascularization. Macroscopic fluorescence imaging showed that Ce6-PVP-induced fluorescence had a higher sensitivity and specificity for delineating tumor from the adjacent normal CAM compared to Ce6 alone. Nonlinear regression analyses have shown that Ce6-PVP has a longer half-life in the tumor compared to Ce6. The uptake ratio of Ce6-PVP was found to have a 2-fold increase across the CAM when compared to that of Ce6, indicating that PVP was able to facilitate diffusion of Ce6 across the membrane. Confocal laser scanning microscopy further confirmed that Ce6-PVP has better penetration in the CAM as well as in the tumor cells compared to Ce6. The present work contributes to our understanding of the Ce6-PVP drug-polymer system by demonstrating for the first time that the presence of PVP facilitates the transport of Ce6 across the chorioallantoic membrane.

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The Current Diagnosis of Superficial Bladder Cancer Must Be Reconsidered

Cited by 7 publications

References 43 publications

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR

Diagnostic accuracy of optical coherence tomography in bladder cancer patients: A systematic review and meta-analysis

Membrane transport enhancement of chlorin e6‐polyvinylpyrrolidone and its photodynamic efficacy on the chick chorioallantoic model

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The Current Diagnosis of Superficial Bladder Cancer Must Be Reconsidered

Cited by 7 publications

References 43 publications

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2nd-TUR

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2nd-TUR

Diagnostic accuracy of optical coherence tomography in bladder cancer patients: A systematic review and meta-analysis

Membrane transport enhancement of chlorin e6‐polyvinylpyrrolidone and its photodynamic efficacy on the chick chorioallantoic model

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Product

Resources

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Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR

Feasibility of Photodynamic Diagnosis for Challenging TUR-Bt Cases Including Muscle Invasive Bladder Cancer, BCG Failure or 2^nd-TUR