“…4,10 A single scan provides an overlap-free 3D visualization of different components of the skull, enables volumetric measurements to be made, and allows a detailed assessment of the maxillofacial structures in variable thickness of the axial, coronal, and sagittal slices, providing real measurements with no magnification. 9,11 Recently, similar to 2D cephalometric tracings, CBCT images can be superimposed, allowing a 3D evaluation of growth changes, treatment effects, and stability over a certain time interval through registration points, angles, shapes, and volumes. [12][13][14] One of the main challenges of 3D superimposition of serial images is to understand that linear/angular measurements in 2D and 3D images are not directly comparable because of differences in size, shape, and relative spatial location of the skeletal, dental, and soft tissue between the two imaging systems.…”