Abstract. Although anthropogenic dust has received more attention from the climate research community, its dominant role in the production process is still not identified. In this study, we analysed the relationship between anthropogenic dust and population density/change over global semi-arid regions and found that semi-arid regions are major source regions in producing anthropogenic dust. The results showed that the relationship between anthropogenic dust and population is more obvious in cropland than in other land cover types (crop mosaics, grassland, and urbanized regions) and that the production of anthropogenic dust increases as the population density grows to more than 90 persons km −2 . Four selected semi-arid regions, namely East China, India, North America, and North Africa, were used to explore the relationship between anthropogenic dust production and regional population. The most significant relationship between anthropogenic dust and population occurred in an Indian semi-arid region that had a greater portion of cropland, and the high peak of anthropogenic dust probability appeared with 220 persons km −2 of population density and 60 persons km −2 of population change. These results suggest that the influence of population on production of anthropogenic dust in semi-arid regions is obvious in cropland regions. However, the impact does not always have a positive contribution to the production of anthropogenic dust, and overly excessive population will suppress the increase of anthropogenic dust. Moreover, radiative and climate effects of increasing anthropogenic dust need more investigation.