The Design and Simulation of HPLC’s Structure

Abstract

Abstract. As an important part of chromatography instruments, chromatographic column plays an important role in the progress of science and the development of production. In order to avoid the traditional process ,design -processing-test -Fixed design -re-processing and effectively shorting the design cycle save a lot of manpower, material and financial resources. This paper offers to watch the changes of flow profile within the column by the application of simulation software ANSYS CFX .Besides, according to the distribution of flow profile, the traditional column has been done a lot of dynamic simulation, especially the stigma part of the column. From a fluid Machinery perspective, we simulated and designed the structure, and then found out the best separation efficiency of the column structure.