The Development of Circadian Rhythms in Infants

Hellbruegge, T

doi:10.1101/sqb.1960.025.01.032

Cited by 129 publications

(44 citation statements)

References 9 publications

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“…One very brief feeding period late at night, perhaps instigated by the mother, since the baby was not awake, was not associated with any increase in temperature. The infant studied was 3 months of age, and might be expected to have begun to develop a circadian rhythm in body temperature and feeding (20,21). Meals and temperature fluctuations did all occur during the day time period, and a gradual decline in temperature at night is apparent in this study.…”

Section: Evidence For the Occurrence In Newborn Infants Of The Eventsmentioning

confidence: 99%

Does Thermoregulatory Feeding Occur in Newborn Infants? A Novel View of the Role of Brown Adipose Tissue Thermo genesis in Control of Food Intake

Himms‐Hagen

1995

Obesity Research

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HIMMS-HAGEN, JEAN. Does thermoregulatory feeding occur in newborn infants? A novel view of the role of brown adipose tissue thermogenesis in control of food intake. Obes Res. 1995;3:361-369. The physiological significance of the extensive deposits of brown adipose tissue (BAT) in newborn human infants has been the subject of much experimentation and discussion. Because of its large thermogenic capacity, its function has usually been viewed as preparing the infant for producing heat in response to cold exposure at birth. Newborn infants are indeed capable of precise thermoregulation for a limited time over a rather limited range of ambient temperatures, from thermoneutrality (32-34'C) down to common "room" temperatures (24-28'C). During such mild "cold-exposure", in response to a decrease in their skin temperature, their sympathetic nervous system activity increases, and they can more than double their resting metabolic rate, principally by thermogenesis in their BAT. This review puts forward an entirely new role for BAT thermogenesis in the cyclic feeding pattern of newborn infants during their first months of life. BAT thermogenesis is proposed to be an integral element in a physiological thermoregulatory feeding control mechanism in which extended periods of very gradual cooling are interspersed with episodes of increased sympathetic nervous system activity, increased heating via BAT thermogenesis, arousal, and feeding. The cry with which the baby attracts its mother's attention is an integral part of the mechanism, as is the nutritive suckling reflex and the behavior of the mother. Initiation of feeding is attributed to a transient dip in blood glucose concentration that is due to stimulation of glucose utilization in the BAT. Termination of feeding is attributed to the high temperature brought about by the stimulated BAT thermogenesis. The duration of the urge to feed extends from the time of the cry to the time of the peak rise in temperature, when feeding stops. There is no clear circadian rhythm in core temperature in newborn infants, and meals occur at fairly frequent intervals both day and night in infants that are fed on demand. These physiological mechanisms are consistent with the limited information on phenomena attending spontaneous feeding in the newborn human infant and with what is known about the physiological control of feeding in rats. In rats, thermoregulatory feeding is defined as a feeding episode that occurs during a transient but marked increase in sympathetic nervous system activity that has several consequences.It stimulates BAT thermogenesis and increases body temperature. It produces a transient decline in blood glucose concentration secondary to the increased uptake of glucose by the stimulated BAT; this signals the initiation of the feeding episode. Subsequently the high temperature induced by BAT thermogenesis signals termination of the feeding episode. The size of the meal is determined by the balance between the capacity for BAT thermogenesis (heat production) and ambie...

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Section: Evidence For the Occurrence In Newborn Infants Of The Eventsmentioning

confidence: 99%

Does Thermoregulatory Feeding Occur in Newborn Infants? A Novel View of the Role of Brown Adipose Tissue Thermo genesis in Control of Food Intake

Himms‐Hagen

1995

Obesity Research

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“…Freud, 1953). Enfin, dans le domaine du développement de l'enfant, l'on s'est attaché à décrire les propriétés du sommeil infantile, l'établisse ment progressif du cycle nycthéméral (Kleitman et Engelmann, 1953 ;Gesell et Amatruda, 1954 ;Debré et Doumic, 1959 ;Hellbrügge, 1959Hellbrügge, , 1960Hellbrügge et al, 1963) ainsi que la fréquence et les relations des troubles du sommeil chez le petit enfant (Moore et Ucko, 1957 ;Soulé, 1958;Kreisler, 1958;Harms, 1964).…”

Section: B Le Sommeil Des Enfantsunclassified

Contribution a l'etude du developpement de l'enfant. Aspects medico-sociaux et psychologiques

Sand¹,

Graffar²

1968

Population (French Edition)

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“…An identical trend was observed at two and three months of age. At three months, however, the minimum respiratory rate was sustained across two intervals in AS and occurred during the third interval in IN, manifestations of increased maturity (12).…”

Section: Emergence Of Circadian Patternsmentioning

confidence: 99%

“…Therefore, death must occur between midnight and 9:00 A.M., and autopsy reports have identified the morning hours shortly before normal waking as the most likely time of death (3,33). A circadian pattern in heart rate and temperature emerges at six wk of age and coincides with the vulnerable age for SIDS (12).…”

mentioning

confidence: 99%

The Emergence of a Circadian Pattern in Respiratory Rates: Comparison between Control Infants and Subsequent Siblings of SIDS

et al. 1980

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The Development of Circadian Rhythms in Infants

Cited by 129 publications

References 9 publications

Does Thermoregulatory Feeding Occur in Newborn Infants? A Novel View of the Role of Brown Adipose Tissue Thermo genesis in Control of Food Intake

Does Thermoregulatory Feeding Occur in Newborn Infants? A Novel View of the Role of Brown Adipose Tissue Thermo genesis in Control of Food Intake

Contribution a l'etude du developpement de l'enfant. Aspects medico-sociaux et psychologiques

The Emergence of a Circadian Pattern in Respiratory Rates: Comparison between Control Infants and Subsequent Siblings of SIDS

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