The diagnosis of contrast-induced neurotoxicity

Kocabay, Gönenç; Karabay, Can Yücel

doi:10.1177/1708538113487334

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…Diagnosis is undertaken by demonstrating typical CT findings in a symptomatic patient when ischemic or hemorrhagic stroke has been excluded. [5] Chronic hypertension is the most important risk factor for the development of CIE, as it predisposes the patient to cerebral autoregulation dysfunction and facilitates disruption of the BBB. Others risk factors are renal failure, diabetes mellitus, previous reactions to contrast agents, intracranial pathology, and the use of a large volume of contrast medium.…”

Section: Discussionmentioning

confidence: 99%

Contrast-induced encephalopathy and permanent neurological deficit: A case report and literature review

Cristaldi

Polistena

Patassini

et al. 2021

Surgical Neurology International

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Background: Contrast-induced encephalopathy (CIE) is a rare condition that occurs after intravenous or intra-arterial contrast agent administration. Patients generally show different ranges of neurological deficits, which generally resolve themselves spontaneously within 24–48 h or in rare cases within 2 weeks. Case Description: We report a case of CIE in a 54-year-old woman during retreatment for recanalization of communicating anterior artery aneurysm and with no history of allergic reaction to contrast agent. After the procedure, the patient developed right hemiplegia and complete aphasia; an MRI performed at 6 days excluded any signs of new ischemia and revealed a hyperintense signal on FLAIR sequences in the left cortical precentral gyrus corresponding to a hyperintense signal on DWI, suggesting a vasogenic edema. After 6 months, she clinically improved even if her previous neurological status was never restored while radiological findings did not change. Conclusion: According to the literature, many risk factors may play a role in the pathogenesis of CIE: we hypothesized that, among all of them, chronic hypertension and previous cerebral ischemic lesions were the most important in our case. Further studies are necessary to find the correlation between possible risk factors and neurotoxicity.

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Section: Discussionmentioning

confidence: 99%

Contrast-induced encephalopathy and permanent neurological deficit: A case report and literature review

Cristaldi

Polistena

Patassini

et al. 2021

Surgical Neurology International

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“…Diagnosis of contrast encephalopathy should be made by CT findings and clinical symptoms. [5] Iodinated contrast encephalopathy may have been induced by cerebral angiography following cerebral ischemia and subsequent use of a contrast agent in our patient. The mechanisms of contrast encephalopathy are unclear.…”

Section: Discussionmentioning

confidence: 67%

Iodinated contrast encephalopathy after coil embolization of unruptured aneurysms

et al. 2018

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Iodinated contrast encephalopathy is known as one of the rare complications of cerebral angiography and neurovascular intervention. The mechanism and causes of contrast encephalopathy are not understood well. In this case, we experienced transient neurological deficit following coil embolization of unruptured aneurysms. A 67-year-old woman with two unruptured aneurysms of internal carotid artery underwent endovascular coil embolization. During the procedure, she presented transient hemiparesis and aphasia. After the treatment, she presented the symptom again, and computed tomography scan showed cortical edema and subarachnoid leakage of contrast agent. Magnetic resonance imaging excluded cerebral infarction. The neurological symptom resolved completely within 24 h after the treatment, and she was diagnosed as the contrast encephalopathy. In our case, we speculated that contrast encephalopathy has occurred subsequently to the transient cerebral ischemia. Iodinated contrast encephalopathy may have induced with neurovascular intervention following cerebral ischemia and increased use of contrast agent. We should consider iodinated contrast encephalopathy when a patient presents hemiparesis and aphasia such as that caused by acute stroke during neurovascular intervention.

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Current knowledge and perspectives of contrast-induced neurotoxicity: A survey of Australian clinicians

Mariajoseph,

Lai,

Moore

et al. 2023

Journal of Clinical Neuroscience

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The diagnosis of contrast-induced neurotoxicity

Cited by 5 publications

References 8 publications

Contrast-induced encephalopathy and permanent neurological deficit: A case report and literature review

Contrast-induced encephalopathy and permanent neurological deficit: A case report and literature review

Iodinated contrast encephalopathy after coil embolization of unruptured aneurysms

Current knowledge and perspectives of contrast-induced neurotoxicity: A survey of Australian clinicians

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