The dietary risk factors on cancer patients receiving chemotherapy and correlation between serum vitamin D and B12 levels, depression and anxiety status

Kacar, Mihrican; Alim, Nural Erzurum

doi:10.20960/nh.04530

Cited by 1 publication

(2 citation statements)

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“…Of course, some studies have reported results contrary to ours. There was no correlation found between depression and anxiety scores and serum vitamin D levels in a study assessing the relationship between serum vitamin D and B12 levels, nutritional levels, depression and anxiety in adult cancer patients before and after chemotherapy ( 13 ). In a study examining the relationship between vitamin D and anxiety and depression in pregnant adolescents, no relationship was found between serum vitamin D and anxiety or depression ( 14 ).…”

Section: Discussionmentioning

confidence: 99%

“…A cohort study from the National FondaMental Expertise Centre (FACE-SZ) found that vitamin D supplementation reduces symptoms of depression and anxiety, but treatment of patients with vitamin D deficiency remains inadequate ( 12 ), other studies did not find a significant association, for example, in a related study evaluating the relationship between serum vitamin D and anxiety in adult cancer patients before and after chemotherapy, no correlation was found between anxiety scores and serum vitamin D levels in either group ( p > 0.05). In another study on vitamin D and mental health in pregnant adolescents in Iran, there was no statistically significant association between vitamin D and anxiety ( p > 0.05) ( 13 , 14 ).…”

Section: Introductionmentioning

confidence: 91%

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Association of serum vitamin D with anxiety in US adults: a cross-sectional study

Wen,

Bai,

et al. 2024

Front. Nutr.

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ObjectiveThere have been proposals that vitamin D may be associated with a reduction in the incidence of anxiety disorders. However, the findings thus far have been inconsistent, warranting further investigation. The purpose of this paper is to explore the link between serum vitamin D and anxiety.MethodsData are from the National Health and Nutrition Examination Survey (NHANES) in the United States from 2007 to 2012. Study included a total of 12,232 participants, and through the multivariate logistic regression to study the relationship between serum vitamin D and anxiety, smooth curve fitting is used to study the nonlinear relationship between serum vitamin D levels and anxiety.ResultsSerum vitamin D levels demonstrated a negative correlation with anxiety (p < 0.001). Vitamin D exhibited a significant impact on anxiety (Q4:OR = 0.774, 95% CI: 0.663–0.903, p < 0.01), and this effect remained significant even after adjusting for confounding variables (Q4:OR = 0.781, 95% CI: 0.669–0.912, p < 0.01). Smoothed curve fitting revealed a negative association between serum vitamin D levels and the risk of anxiety, and these findings persisted after accounting for confounding variables.ConclusionSerum vitamin D levels were inversely associated with anxiety risk in US adults. In the future, more accurate prospective studies are needed to confirm this result.

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Section: Discussionmentioning

confidence: 99%