“…These patients usually had obvious evidence of cardiac and renal insufficiency as well as hypertensive retinopathy, and, despite the similarities, should not be confused with cases of intracranial neoplasm. Riley and Elsberg (1926), Grant (1932), Vallat (1938), and Cruz (1952), have, however, discussed the possibility, and Jefferson (1955) has considered the clinical, radiological, and electroencephalographic differences between hypertensive brain disease and cerebral tumour. When the brain in this type of malignant hypertension is examined carefully, oedema, scattered minute haemorrhages, and areas of softenings have been detected (Rosenberg, 1940;Scheinker, 1943).…”