THE DISABILITY OF JAMES VI &amp; I

Beasley, A. W.

doi:10.1080/0268117x.1995.10555396

Cited by 4 publications

(6 citation statements)

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“…James’s medical complaints have been described in detail, although their interpretation has been controversial (Aitkin, 1822; Beasley, 1995; Holmes, 2003). There are consistent reports of delayed walking until the age of 5–7 years, with persistent weakness of his legs throughout his life (Chambers, 1830a).…”

Section: Medical History Of James Vi/i (See Table 2)mentioning

confidence: 99%

“…The weakness in the lower limbs with delayed, and difficulty in, walking has been attributed to rickets (Holmes, 2003) and blamed on his alcoholic wet nurse, Helen Litell (Chambers, 1830a; De Mayerne, 1623; McElwee, 1958). However, Beasley (1995) suggested from portraits and associated features that the King had mild cerebral palsy (Little’s disease) rather than rickets, in addition to acute porphyria.…”

Section: Previous Proposals Of the Basis To James’s Medical Conditionsmentioning

confidence: 99%

“…His medical history has generated recurrent dispute and may be highly relevant to his varied policies and actions and his responses to life’s events. The starting point for this study followed previous work (Peters and Beveridge, 2010; Peters and Wilkinson, 2010) on the nature of King George III’s mental disorder, claimed to have been due to acute porphyria (Macalpine and Hunter, 1969), a view that has been repeatedly re-stated (Beasley, 1995; Fraser, 1974; Röhl, Warren and Hunt, 1998; Smith, 1973; Rutherford, 2010; Trevor-Roper, 2006; Watkin, 2004). It has also been repeatedly claimed that the origin of the porphyria suffered by George III can be attributed to the disease in James VI/I and his immediate relatives (Cox et al, 2005; Hurst, 1982; Macalpine, Hunter and Rimington, 1968; Rushton, 2008).…”

Section: Introductionmentioning

confidence: 99%

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The nature of King James VI/I’s medical conditions: new approaches to the diagnosis

2012

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It has been claimed that King James VI/I, an antecedent of King George III, suffered from acute porphyria, and that the disease was passed on to George III through his grand-daughter Sophie, mother of George I. The life of James is reviewed and previously-proposed diagnoses are considered. James's medical history is discussed in detail and, where possible, examined with validated symptom scales. Using an online database of neurological diseases, the authors show that James's symptomatology is compatible with a diagnosis of Attenuated (mild) Lesch-Nyhan disease; no evidence was found to support a diagnosis of acute porphyria. In addition, there is evidence of associated Asperger traits which may explain some of the King's unusual behavioural and psycho-social features.

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Section: Medical History Of James Vi/i (See Table 2)mentioning

confidence: 99%

Section: Previous Proposals Of the Basis To James’s Medical Conditionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The nature of King James VI/I’s medical conditions: new approaches to the diagnosis

2012

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“…Additional evidence may also support this proposal. Although King James VI/I was reported to be cognitively normal or even gifted, and he did not exhibit self-injurious behaviour characteristic of classic Lesch-Nyhan disease, he did have a reputation for bad behaviour (Beasley, 1995). He was constantly 'restless', and prone to unexpected aggression or moodiness.…”

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confidence: 99%

Reply: Attenuated variants of Lesch-Nyhan disease: the case of King James VI/I

Jinnah

Schretlen

2010

Brain

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“…Therefore I agree with Milo Keynes' closing paragraph and was interested to read Graham Brack's thoughtful letter in the August JRSM. 2 As he indicates, Holmes' spelling of the surname is incorrect; Mary Queen of Scots was brought up in France from babyhood and married the Dauphin as Marie Stuart. The spelling in this country was always Stewart-from King Robert II, the Steward.…”

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confidence: 99%

The Sickly Stuarts

Beasley¹

2004

J R Soc Med

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A one-handed method for obtaining arterial blood Reporting a high rate of needle-stick injuries, Mr Elmiyeh and his colleagues (July 2004 JRSM 1) offer no detail on the techniques. I would not be surprised if arterial puncture was overrepresented. Here I describe a one-handed method that might lessen the hazard. The most commonly used method to obtain arterial blood is to palpate for the pulse with fingers from one hand while inserting the needle with the other hand directly juxtaposed or under the fingers from the first hand. This carries risks of needle-sticks if an uncooperative or disoriented patient moves. Another established method is to insert the needle at an anatomical location where arterial pulsations are visible through the skin. This is one-handed, but in many patients it cannot be used because pulses are not visible transcutaneously. My one-handed method works as follows. (1) Palpate for the arterial pulse and mark the approximate location of the pulse with an indentation from the cap of the closed syringe. (2) Again locate the pulse by palpation and make a mental note of its relation (if there is any deviation) from the indented mark. (3) Clean the area with alcohol. (4) Insert the needle with one hand, using the mark as a guide. (5) If the blood is drawn with a safety needle, recap it with one hand.

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THE DISABILITY OF JAMES VI & I

Cited by 4 publications

References 0 publications

The nature of King James VI/I’s medical conditions: new approaches to the diagnosis

The nature of King James VI/I’s medical conditions: new approaches to the diagnosis

Reply: Attenuated variants of Lesch-Nyhan disease: the case of King James VI/I

The Sickly Stuarts

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