2000
DOI: 10.1016/s0723-2020(00)80062-4
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The Discovery of Enfumafungin, a Novel Antifungal Compound Produced by an Endophytic Hormonema Species Biological Activity and Taxonomy of the Producing Organisms

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Cited by 132 publications
(78 citation statements)
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“…Of the 53 isolates screened, antifungal activity was detected in five strains, but by HPLC analysis only two of them were found to produce 66, in amounts similar to the strain ATCC 74360. 41 …”
Section: Metabolites Of Mevalonate Originmentioning
confidence: 99%
“…Of the 53 isolates screened, antifungal activity was detected in five strains, but by HPLC analysis only two of them were found to produce 66, in amounts similar to the strain ATCC 74360. 41 …”
Section: Metabolites Of Mevalonate Originmentioning
confidence: 99%
“…In previous works, there have been some reports on the antimicrobial (Tanaka, Fukushima, Tsujiro, & Fujimori, 1997;Gong & Guo, 2009;Du, Li, Li, Shang, & Wang, 2012), antioxidant (Huang, Chen, Chang, Sheu, & Lin, 2007;Dhankhar, Kumar, Dhankhar, & Yadav, 2012;Nath, Raghunatha, & Joshi, 2012), anti-inflammatory (Deshmukh et al, 2009;Pretsch et al, 2014) activity of the endophytic fungi. Besides, some in vivo studies on the anti-cancer, anti-diabetic and other bioactivity (Konrath et al, 2012;Govindappa et al, 2015;Tan et al, 2015) have been evidenced, but in vivo antimicrobial studies on endophytic fungi are very scarce (Peláez et al, 2000;Nath & Joshi, 2016).In the present study, we aimed to identify C. gigantea fungal endophytes and to characterize their anti-candidal activity in an in vivo model. …”
mentioning
confidence: 91%
“…En 1989, se reportó el precursor de caspofungina (MK991) 11 y en 1990 el de micafungina (FK463) 12 . Se han descrito varios otros análogos y derivados de equinocandinas; la enfumafungina, las arbocandinas, las papulacandinas, la pneumocandina B, la arundifungina y la mulucandina [13][14][15][16][17] . Otras como la cilofungina han sido abandonadas en su desarrollo clínico dada su difícil formulación y gran toxicidad.…”
Section: El Génesis De Las Equinocandinasunclassified