The distribution of muscle primary afferents from the masseter nerve to the trigeminal sensory nuclei

Nishimori, Toshikazu; Sera, M.; Suemune, Setsuko; Yoshida, Atsushi; Tsuru, K.; Tsuiki, Yutaka; Akisaka, Toshitaka; Okamoto, Takashi; Dateoka, Yoichi; Shigenaga, Yoshio

doi:10.1016/0006-8993(86)91148-0

Cited by 69 publications

(33 citation statements)

References 28 publications

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“…Some previous neuroanatomical tracing studies have reported a projection of Vme neurons to Vc (Nishimori et al, 1986;Shigenaga et al, 1988b;Arvidsson and Raappana, 1989). It is not clear in these nonspecific studies, however, how labeled fibers from trigeminal ganglion afferents were differentiated from fibers of Vme neurons.…”

Section: The Projection Of Jaw-muscle Spindle Afferents To the Caudalmentioning

confidence: 92%

Projection of jaw‐muscle spindle afferents to the caudal brainstem in rats demonstrated using intracellular biotinamide

Luo

Wong

Dessem

1995

J of Comparative Neurology

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Intracellular staining with biotinamide was used to study the axonal projection and synaptic morphology of rat jaw-muscle spindle afferents. Intracellular recordings in the mesencephalic trigeminal nucleus (Vme) were identified as spindle afferent responses by their increased firing during stretching of the jaw-elevator muscles. Biotinamide-stained axon collaterals with boutons were found in the trigeminal motor nucleus (Vmo), Vme, the region dorsal to Vmo including the supratrigeminal region, the dorsomedial portion of the trigeminal principal sensory nucleus, and the dorsomedial part of the rostral spinal trigeminal subnucleus oralis. Additional, previously undescribed projections of jaw-muscle spindle afferents were found to the dorsomedial portion of the caudal spinal trigeminal subnucleus oralis (Vodm), the dorsomedial part of the spinal trigeminal subnucleus interpolaris (Vidm), the caudal parvicellular reticular formation, laminae IV and V of the spinal trigeminal subnucleus caudalis (Vc), and the dorsal division of the medullary reticular field. Labeled spindle boutons in Vodm formed predominately axodendritic synapses. Some of these boutons received presynaptic inputs from unlabeled P-type boutons containing clear, spherical, or flattened vesicles. In Vidm, labeled collaterals and boutons were densely clustered into glomerular-like structures. Labeled boutons in Vidm made axodendritic, axosomatic, and axoaxonic synapses and received synaptic contacts from unlabeled boutons containing clear, spherical, or flat and pleomorphic vesicles. Unlabeled presynaptic boutons in Vidm occasionally contained dense core vesicles. Labeled boutons in Vc mainly formed synaptic contacts with large diameter dendrites. This projection of jaw-muscle spindle afferents to caudal brainstem regions may play a significant role in masticatory-muscle stretch reflexes and in the integration of trigeminal proprioceptive information and its transmission to higher centers.

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Section: The Projection Of Jaw-muscle Spindle Afferents To the Caudalmentioning

confidence: 92%

Projection of jaw‐muscle spindle afferents to the caudal brainstem in rats demonstrated using intracellular biotinamide

Luo

Wong

Dessem

1995

J of Comparative Neurology

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“…The lateral part of the external medial subnucleus receives input from the caudal two-thirds of the NTS and the adjacent area postrema (Herbert et al, 1990;Feil and Herbert, 1995). Projections from the PTN are superimposed on such inputs and may relay information of both visceral (Altschuler et al, 1989;Panneton, 1991) and somatic (Marfurt, 1981;Panneton and Burton, 1981;Arvidsson and Thomander, 1984;Nishimori et al, 1986;Shigenaga et al, 1986Shigenaga et al, , 1988Pfaller and Arvidsson, 1988;Neuhuber and Zenker, 1989;Arvidsson and Pfaller, 1990) origin.…”

Section: Efferent Connections Of the Ptnmentioning

confidence: 98%

“…Neuroanatomical studies have shown that the PTN receives input from the periphery through cranial nerves V (Nishimori et al, 1986;Shigenaga et al, 1986Shigenaga et al, , 1988Pfaller and Arvidsson, 1988;Panneton, 1991), IX, and X Mizuno, 1982, 1983;Arvidsson and Thomander, 1984;Hamilton and Norgren, 1984;Altschuler et al, 1989;Nazruddin et al, 1989). Afferent projections coursing in branches of the facial nerve, which have their cell bodies in the nodose ganglion, also terminate in the PTN (Arvidsson and Thomander, 1984).…”

mentioning

confidence: 96%

Efferent and collateral organization of paratrigeminal nucleus projections: An anterograde and retrograde fluorescent tracer study in the rat

Saxon

Hopkins

1998

J. Comp. Neurol.

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The paratrigeminal nucleus (PTN) receives primary visceral afferent projections through cranial nerves IX and X and somatic afferent projections through cranial nerve V and dorsal roots as far caudally as C7. Pressure injections of the anterograde tracer tetramethylrhodamine dextran into the PTN in the rat resulted in bilateral labeling in the nucleus of the tractus solitarius, dorsal motor nucleus of the vagus nerve, and parabrachial nucleus. Anterograde labeling in the parabrachial nucleus was strongest in the external medial, external lateral, and ventral lateral subnuclei. Anterograde labeling was also found in the contralateral paratrigeminal nucleus, lamina I of the spinal trigeminal nucleus subnucleus caudalis, and ventroposteromedial nucleus of the thalamus. The collateral organization of PTN neurons was demonstrated by injecting different fluorescent retrograde tracers into the terminal fields of PTN projections as determined by the anterograde tracing experiments. Double-labeled neurons were found in the paratrigeminal nucleus following all combinations of injection sites. The most prominent PTN efferent projections and the most highly collateralized were to the nucleus of the tractus solitarius and parabrachial nucleus. The efferent and collateral connections of the paratrigeminal nucleus may provide a neuroanatomical substrate for integrating convergent visceral and somatic afferent information used to modulate autonomic function and behavior related to thermoregulation, nociception, and gustation.

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“…Periodontal and spindle afferents (Dessem and Taylor 1989;Jerge 1963;Mizuno 1970;Nishimori et al 1986;Nomura and Mizuno 1985;Shigenaga et al 1989) and orofacial afferents (Goldberg 1972;Sessle 1977) facilitate jaw-closing muscle activity and the SupV is a recipient of such afferents. Therefore it is possible that excitatory glutamatergic premotor neurons in the SupV are involved in increasing jaw-closing muscle activity via sensory inputs during mastication.…”

Section: Roles Of Premotor Neurons In the Supvmentioning

confidence: 99%

“…The SupV receives abundant orofacial sensory inputs, including periodontal and spindle afferents (Dessem and Taylor 1989;Jerge 1963;Mizuno 1970;Nishimori et al 1986;Nomura and Mizuno 1985;Shigenaga et al 1989) and descending inputs from the cortical masticatory area (Hatanaka et al 2005;Yasui et al 1985). Retrograde axonal tracing studies have shown that premotor neurons targeting the MoV are present in the SupV (Landgren et al 1986;Mizuno et al 1983;Travers and Norgren 1983;Turman Jr and Chandler 1994a,b).…”

Section: Introductionmentioning

confidence: 99%

Synaptic Transmission From the Supratrigeminal Region to Jaw-Closing and Jaw-Opening Motoneurons in Developing Rats

Nakamura

Inoue²,

Nakajima³

et al. 2008

Journal of Neurophysiology

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The distribution of muscle primary afferents from the masseter nerve to the trigeminal sensory nuclei

Cited by 69 publications

References 28 publications

Projection of jaw‐muscle spindle afferents to the caudal brainstem in rats demonstrated using intracellular biotinamide

Projection of jaw‐muscle spindle afferents to the caudal brainstem in rats demonstrated using intracellular biotinamide

Efferent and collateral organization of paratrigeminal nucleus projections: An anterograde and retrograde fluorescent tracer study in the rat

Synaptic Transmission From the Supratrigeminal Region to Jaw-Closing and Jaw-Opening Motoneurons in Developing Rats

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