The early complications of cataract surgery

McKellar, Malcolm J.; Elder, Mark

doi:10.1016/s0161-6420(00)00431-0

Cited by 54 publications

(14 citation statements)

References 22 publications

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“…[23] Surgically, cataractous lens can be replaced by artificial lens; however, epidemiologically the problem is not reduced owing to expense and post-operational complications of surgery. [24] For these reasons, the present study focused on a pharmacological intervention for cataract, in particular, scientific validation of Triphala in the treatment of cataract.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Gupta¹,

Kalaiselvan²,

Srivastava³

et al. 2010

J Ayurveda Integr Med

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Triphala (TP) is composed of Emblica officinalis, Terminalia chebula, and Terminalia belerica. The present study was undertaken to evaluate its anticataract potential in vitro and in vivo in a selenite-induced experimental model of cataract. In vitro enucleated rat lenses were maintained in organ culture containing Dulbecco’s Modified Eagles Medium alone or with the addition of 100μM selenite. These served as the normal and control groups, respectively. In the test group, the medium was supplemented with selenite and different concentrations of TP aqueous extract. The lenses were incubated for 24 h at 37°C. After incubation, the lenses were processed to estimate reduced glutathione (GSH), lipid peroxidation product, and antioxidant enzymes. In vivo selenite cataract was induced in 9-day-old rat pups by subcutaneous injection of sodium selenite (25 μmole/kg body weight). The test groups received 25, 50, and 75 mg/kg of TP intraperitoneally 4 h before the selenite challenge. At the end of the study period, the rats’ eyes were examined by slit-lamp. TP significantly (P < 0.01) restored GSH and decreased malondialdehyde levels. A significant restoration in the activities of antioxidant enzymes such as superoxide dismutase (P < 0.05), catalase (P < 0.05), glutathione peroxidase (P < 0.05), and glutathione-s-transferase (P < 0.005) was observed in the TP-supplemented group compared to controls. In vivo TF 25mg/kg developed only 20% nuclear cataract as compared to 100% in control. TP prevents or retards experimental selenite-induced cataract. This effect may be due to antioxidant activity. Further studies are warranted to explore its role in human cataract.

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Section: Discussionmentioning

confidence: 99%

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Gupta¹,

Kalaiselvan²,

Srivastava³

et al. 2010

J Ayurveda Integr Med

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“…1 Also in the same period, in Scotland, 2 a hospital infection control team reported more acute PE than expected after cataract surgery, according to the normal incidence. 3 Among the many risk factors involved in the PE pathogenesis, [4][5][6][7][8][9][10][11] it is difficult to assess the weight of climatic influence; however, as conjunctival bacteria are the main source of contamination in cataract surgery, 12,13 it is quite logical to expect that the prevalence of conjunctival bacteria determines the prevalence of the infectious PE. Today, the world-wide use of povidona iodine solution as a preoperative prophylaxis in cataract extraction 14 could provide homogeneity in the kind of bacteria that produce PE all over the world, which was impossible to detect when a great number of different prophylactic techniques were used.…”

Section: Introductionmentioning

confidence: 99%

Climatic influence on conjunctival bacteria of patients undergoing cataract surgery

Rubio

2004

Eye

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“…The incidence of early postoperative IOP increase is reported to be 2.3%–8.9% in all cataract extractions 21. In another study, Kim et al found more frequent (22.0%) increased IOP on the first postoperative day following cataract surgery 22.…”

Section: Discussionmentioning

confidence: 99%

Results of cataract surgery in the very elderly population

Michalska-Małecka¹,

Nowak²,

Gościniewicz³

et al. 2013

CIA

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AimThe aim of our study was to retrospectively evaluate the effectiveness and safety of cataract surgery and intraocular lens implantation (IOL) for patients aged 90 years or older, whom we define as “very elderly.”MethodsThe study involved a total number of 122 patients (122 eyes) with senile cataracts. The mean age of patients was 91.2 ± 2.3 years (range 90–100 years old). Phacoemulsification (phaco) was done on 113 of 122 eyes, and 9 of 122 eyes had extracapsular cataract extraction (ECCE). Postoperative visual acuity and intraocular pressure (IOP) were analyzed on the first postoperative day, 3 months after surgery, and 6 months after surgery.ResultsBest corrected visual acuity (BCVA) improved in 100 of 122 eyes (82.0%). BCVA remained the same in 20 of 122 eyes (16.4%) and decreased in 2 of 122 eyes (1.6%), mainly because of coexisting age-related macular degeneration (AMD). The BCVA 3 months after surgery was ≥0.8 in 23 of 122 eyes (18.9%), between 0.5 and 0.7 in 28 of 122 eyes (22.3%), and between 0.2 and 0.4 in 33 of 122 eyes (27.1%). We found significant implications of cataract surgery on decreasing IOP in the studied group of patients suffering from glaucoma compared to the patients without glaucoma.ConclusionAdvanced age is not a contraindication for cataract surgery. The results of the study showed that when systemic conditions are stable, both phaco and ECCE with IOL for very elderly patients are effective and safe.

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The early complications of cataract surgery

Cited by 54 publications

References 22 publications

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies

Climatic influence on conjunctival bacteria of patients undergoing cataract surgery

Results of cataract surgery in the very elderly population

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