The Earth: A Lost Planet from another Universe

Simeon, Joseph Oyepata

doi:10.47191/ijmra/v4-i12-04

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…A low red blood cell (RBC) count can result in a wide range of symptoms and medical issues (Sabastine et al, 2021;Tosin et al, 2021).The blood's hemoglobin helps carry oxygen from your lungs to your tissues. In muscle cells, myoglobin takes up, stores, transports, and releases oxygen (Oyepata 2021). Additionally, the extract had no effect on the amount of basophiles, neutrophils, eosinophils, or lymphocytes.…”

Section: Discussionmentioning

confidence: 97%

“…Serum/plasma urea concentration reflects the balance between urea production in the liver and urea elimination by the kidneys. An increased in plasma/serum urea can be caused by increased urea production, decreased urea elimination which affects the glomerular filtration rate, or a combination of the two (Oyepata and Simeon 2022;Maton et al, 1993). Result of the study suggests that the extract does not increase protein breakdown and has little significant on glomerular filtration rate.…”

Section: Discussionmentioning

confidence: 99%

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Toxicological studies of ethanol leaf extract of Lavandulastoechas on kidney of Wistar rat.

Joseph

2023

jcbr

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The medicinal ingredients in herbal remedies are derived from plants. Despite the fact that they could offer a wide range of health advantages, they are thought to have a lower likelihood for adverse effects. The medicinal herb lavender (Lavandulastoechas L.) is widely utilized for a variety of medical conditions. The aim of this investigation is to evaluate the toxicological effect of Lavandulastoechas on Wistar rat kidney.Twenty four (24)Animals of either sex were used. Group 1 was given distilled water (10 ml/kg), while groups 2, 3, and 4 were given 50, 100, and 200 mg/kg of Lavandulastoechas, respectively for 28 days. Animals were housed in typical cages and given oral access to the extract for 28 days before being weighed and put to death. A heart puncture was used to get blood, which was then promptly taken for testing.Red blood cell, Hemoglobin, and Mean corpuscular volume levels decreased significantly (P<0.05), but neutrophils, basophiles, eosinophils, and platelets remained constant. At 100 and 200 mg/kg, Lavandulastoechas significantly (P<0.05)loweredK+ levels. Na+ increased significantly (P<0.05)at a dosage of 200 mg/kg. Across doses given, the levels of creatinine, chloride, and urea were not substantially (P<0.05)impacted. A histological analysis shows minimal tubular deformation.The study's findings indicated that the plant might have a negligible impact on the kidney, indicating that it should be used with caution if consumed over an extended period of time.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Toxicological studies of ethanol leaf extract of Lavandulastoechas on kidney of Wistar rat.

Joseph

2023

jcbr

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“…When there is lower red blood count than is normal, the body has to work harder to get enough oxygen to the cells. A low red blood cell (RBC) count can cause a variety of symptoms and health complications [47][48][49][50] . Hemoglobin is essential for transferring oxygen in your blood from the lungs to the tissues.…”

Section: Discussionmentioning

confidence: 99%

“…This may be due to disruptive effect of the plant. An increase creatinine level can be observe in some kidney diseases, due to loss of normal excretory function of the creatinine [53][54][55][56][57] , when there is a muscular cells damage or following an incompatable medication interfering with the normal functioning of the kidney [58][59] . Creatinine, is mostly derived from endogenous sources by tissue creatinine breakdown 60 .…”

Section: Discussionmentioning

confidence: 99%

"Toxicological Study of Ethanol Extract of Lavandula Stoechas on Kidney of Wistar Rat"

Modupe¹,

Simeon²,

Tosin³

2022

Int. J. Res. Publ. Rev.

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Introduction/Aim: Herbal products are medicinal agents obtained from plants. They are believed to have lesser tendency for side effect in spite of their numerous possible health benefits. Lavender (Lavandula stoechas L.) is a medicinal plant largely used for different medicinal purposes. The aim of this study is to determine the toxicological effect of Lavandula stoechas on the kidney of Wistar rats. Method: Animals of either sex were selected. Group 1 received distilled water (10 ml/kg), while group 2, 3 and 4 received Lavandula stoechas 50, 100 and 200 mg/kg respectively. Animals were kept in standard cages and given access to the extract, water and food orally for 28 days, after which they were weighed and sacrificed. Blood was collected by cardiac puncture and taken immediately for analysis. Result: There was significant (P<0.05) decrease in RBC, HGB, MCV, while there was no change in the level of neutrophiles, basophiles, eosinophiles and platelets. Lavandula stoechas, significantly (p<0.05) caused decreased K+ level at 100 and 200 mg/kg respectively. While there was significant (p<0.05) increase of Na+ at 200 mg/kg dose. Level of Creatinine, chloride and urea were not significantly (p<0.05) affected across doses administered. Histological study reveals slight tubular distortion. Conclusion: The result of the study showed that the plant could have slight effect on the kidney which suggests that the plant should be use with caution when taken for a sustained period of time. Histological study reveals slight tubular distortion.

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Update Report on Progress of COVID-19 Pandemic from 19th-25th January, 2022 Across Different Countries of the World

Simeon¹,

Tosin²,

Zubairu³

2023

Asian J. of Applied Sciences

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The Earth: A Lost Planet from another Universe

Cited by 3 publications

References 7 publications

Toxicological studies of ethanol leaf extract of Lavandulastoechas on kidney of Wistar rat.

Toxicological studies of ethanol leaf extract of Lavandulastoechas on kidney of Wistar rat.

"Toxicological Study of Ethanol Extract of Lavandula Stoechas on Kidney of Wistar Rat"

Update Report on Progress of COVID-19 Pandemic from 19th-25th January, 2022 Across Different Countries of the World

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