Background. In team sports, according to perform variety of motor skills, development of special bio-motor abilities and imposed proper exercise stress, hematologic adaptations following exercise will be different. Objectives. Therefore, the aim of this study was the effects of six weeks combined training program on hematological parameters in elite basketball players. Methods. Fifteen athletes from 30 qualified players for basketball playoff league, with the average age of (24±1/5) years, selected randomly and they were participated in 6weeks (3 sessions per week) of combined training (circular resistance training and basketball special-skills). Blood samples were drawn in the fasting state for Three times: before, after and 24 recovery hours in order to measure the hematologic parameters (red and white blood cells, hemoglobin, hematocrit, MCV, PLT, MCH, MCHC, plasma volume). Results. Significant increase in the white blood cells and platelet counts were obtained, in two stages; after and 24 hours recovery times. While the levels of hemoglobin, hematocrit, and number of red blood cells (RBC) were decreased after 24 hours of recovery significantly. The significant changes weren't observed in MCH, MCHC, MCV and plasma volume factors following the combined training program. Conclusion. Performing combined training plays an important role in physiological and hematological adaptations processes and promotion athletic performance. While, prescription this method of training must be associated with regularly biochemical blood monitoring to balance between exercises stress and recovery strategies.