1990
DOI: 10.1016/0031-9384(90)90105-d
|View full text |Cite
|
Sign up to set email alerts
|

The effect of amiloride analogs on taste responses in gerbil

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
5
0

Year Published

1990
1990
2004
2004

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 25 publications
(6 citation statements)
references
References 23 publications
1
5
0
Order By: Relevance
“…Another mechanism underlying calcium transduction may involve ecto-calcium-dependent ATPase, which is found in taste buds of amphibians and mammals (hamsters) and is related to oral calcium concentrations (9). A role for epithelial Na ϩ /Ca 2ϩ exchange seems unlikely because blockade with 5-(N-4chlorobenzyl)-2Ј,4Ј-dimethylbenzamil had no effect on human subjects' perception of CaCl 2 taste (259).…”
Section: Calcium Transduction: Electrophysiological Evidencementioning
confidence: 99%
“…Another mechanism underlying calcium transduction may involve ecto-calcium-dependent ATPase, which is found in taste buds of amphibians and mammals (hamsters) and is related to oral calcium concentrations (9). A role for epithelial Na ϩ /Ca 2ϩ exchange seems unlikely because blockade with 5-(N-4chlorobenzyl)-2Ј,4Ј-dimethylbenzamil had no effect on human subjects' perception of CaCl 2 taste (259).…”
Section: Calcium Transduction: Electrophysiological Evidencementioning
confidence: 99%
“…3A). neutrophils with apparent K, values of 84, 1.4, 0.44, and0.16 pM, respectively (Schiffman et al, 1990). The results are shown in Fig.…”
Section: Presence Of Na+/h+ Exchange In Chromaffin Cellsmentioning
confidence: 88%
“…There are methodological differences between the present and prior studies. Besides the species difference, Schiffman and colleagues (24) applied the Na ϩ /H ϩ exchange antagonists after a pretreatment regimen, whereas the present study added the antagonist to NaCl during sustained neural activity. Although the Na ϩ /H ϩ exchanger is a ubiquitous protein occurring in multiple isoforms (23,32), our results are merely suggestive and the presence of a Na ϩ /H ϩ exchange protein in taste cell membranes must be verified using other techniques such as patch clamp or immunocytochemistry.…”
Section: Nacl Nerve Responsesmentioning
confidence: 99%
“…The present finding implicating the involvement of a Na ϩ /H ϩ exchange pathway in NaCl transduction is inconsistent with a prior study investigating the role of Na ϩ /H ϩ exchange in NaCl taste. Schiffman et al (24) examined the effect of selective Na ϩ /H ϩ exchange antagonists on taste nerve responses to NaCl and concluded that a Na ϩ /H ϩ exchange pathway was not involved in NaCl transduction in gerbils. There are methodological differences between the present and prior studies.…”
Section: Nacl Nerve Responsesmentioning
confidence: 99%
See 1 more Smart Citation