The effect of antibacterial ingredients and coating microstructure on the antibacterial properties of plasma sprayed hydroxyapatite coatings

Song, Lei; Xiao, Yanfeng; Gan, Lu; Wu, Yao; Wu, Fang; Gu, Zhongwei

doi:10.1016/j.surfcoat.2011.12.034

Cited by 16 publications

(7 citation statements)

References 19 publications

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“…Various techniques have been employed to introduce a silver antibacterial agent into an HAp coating, such as a chemical precipitation method by calcium- and phosphorus-based ion solutions with the addition of AgNO 3 − or by silver doping into plasma-sprayed HAp. , However, HAp synthesized by these techniques is easily dissolved due to the low crystallinity of the coating. The work of Wolke and coauthors revealed that the HAp dissolution is much higher for low-crystallinity coatings, and their observation suggests that the amorphous coating completely dissolved within 4 weeks .…”

Section: Introductionmentioning

confidence: 99%

Bioactive Coating on Ti Alloy with High Osseointegration and Antibacterial Ag Nanoparticles

Sobolev

Valkov

Kossenko

et al. 2019

ACS Appl. Mater. Interfaces

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Titanium alloys have advanced mechanical properties jointly with high biocompatibility that make them eminently suitable for biomedical applications such as dental and orthopedic implants. Improvement in their osseointegration with human bone can be achieved by the development of hydroxyapatite (HAp) on a Ti alloy surface using different methods of deposition. However, plasma electrolytic oxidation (PEO) treatment has been found to be one of the most promising techniques, due to the formation of high bonding between the bone and the Ti surface. Along with this high bonding, an antibacterial ability of the surface to prevent bacterial infection is also essential. Silver, which is a widely applicable antibacterial agent, was used in this work. First, a titanium oxide coating containing calcium and phosphorus and Ag nanoparticles was formed by PEO treatment. Then, Ti alloy was subjected to hydrothermal treatment to ensure a crystalline formation of HAp. Morphology and phase composition investigations detected the presence of HAp crystals in the coating along with antibacterial agents of silver nanoparticles. The biocompatibility and bioactivity of the created coating were examined by contact angle (CS) measurement and electrochemical impedance spectroscopy (EIS). It was shown that the coating was extensively grown after exposure of the alloy to simulated body fluid (SBF) solution for 7 days with no effect on the Ag nanoparticles. An antibacterial test using Staphylococcus aureus and Escherichia coli revealed that the coating containing Ag nanoparticles has more significant antibacterial effectiveness compared to a coating that does not contain silver.

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Section: Introductionmentioning

confidence: 99%

Bioactive Coating on Ti Alloy with High Osseointegration and Antibacterial Ag Nanoparticles

Sobolev

Valkov

Kossenko

et al. 2019

ACS Appl. Mater. Interfaces

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“…Material surface property to prevent bacterial attachment HA nanorods obtained by green synthesise, 134 Ag/HA, [135][136][137][138][139][140][141] Ag/ CNT/HA, 142 CNT/CeO 2 /Ag/HA, 143 graphene, [144][145][146] nanodiamond (ND), 147 TiO 2 /HA, 148 SrO/Ag 2 O/HA, 149 Sr/Ag/HA and TiO 2 bilayer, 109 Ag/ZnO/HA, 117 Amino-acid/HA/TiO 2 , 150 Sr/Zn/HA, 151 Ag/Zn/HA/polydimethylsiloxanes, 115 AgNO 3 sterilized on HA, 152 Ag-HA/poly-ether-ether-ketone (PEEK), 153 HA/tryptophan/ TiO 2 , 154 TiO 2 nanotube, 121,155 Ag/nano-TiO 2 , 121 chitosan, 156 ZnO/ultra high molecular weight polyethylene (UHMWPE), 157 silk fibroin/tannic acid/HA, 158 and others 5,159-163 Bioactive and bioactive fixation Supportive response of the material to perform biological functions. In the permanent implantation, a firm chemical and biological bond formation at the junction of material surface and tissue interface.…”

Section: Anti-bacterialmentioning

confidence: 99%

“…Reinforcing with Cu, Ag, and Zn provides antibacterial and anti-inflammatory properties to HA-coated implants. 250 There have been several reports on the addition of silver, 42,138,141,149,152,156,190,195,341-347 strontium, 97,149,151,165,168,196,281,[348][349][350] magnesium, 189,196,274,281,351,352 and other materials 27,79 to HA. A summary of these studies showing the relevance of these reinforcements to enhance coating properties is given in Table 9.…”

Section: Metal Ion-reinforced Ha Composite Coatingsmentioning

confidence: 99%

Bioactive surface modifications through thermally sprayed hydroxyapatite composite coatings: a review of selective reinforcements

et al. 2022

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“…However, these methods are not only prone to drug resistance, but also usually have a burst phase at the initial stage of drug release, which prevents long-term antibacterial effects. Many methods have also been performed to introduce inorganic antibacterial metal elements to titanium surfaces, such as plasma spraying [11], micro-arc oxidation [12], and ultrasonic spray coating [3]. Compared with organic antibacterial drugs, metal elements exhibit broad-spectrum antibacterial activity, long acting time, and no drug resistance.…”

Section: Introductionmentioning

confidence: 99%

Mussel-Inspired Carboxymethyl Chitosan Hydrogel Coating of Titanium Alloy with Antibacterial and Bioactive Properties

et al. 2021

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Infection-related titanium implant failure rates remain exceedingly high in the clinic. Functional surface coating represents a very promising strategy to improve the antibacterial and bioactive properties of titanium alloy implants. Here, we describe a novel bioactive surface coating that consists of a mussel-inspired carboxymethyl chitosan hydrogel loaded with silver nanoparticles (AgNPs) to enhance the bioactive properties of the titanium alloy. The preparation of hydrogel is based on gallic acid grafted carboxymethyl chitosan (CMCS-GA) catalyzed by DMTMM (4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride). To build a firm bonding between the hydrogel and titanium alloy plate, a polydopamine layer was introduced onto the surface of the titanium alloy. With HRP/H2O2 catalysis, CMCS-GA can simply form a firm gel layer on the titanium alloy plate through the catechol groups. The surface properties of titanium alloy were characterized by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), and water contact angle. Silver nanoparticles were loaded into the gel layer by in situ reduction to enhance the antibacterial properties. In vitro antibacterial and cell viability experiments showed that the AgNPs-loaded Ti-gel possesses excellent antibacterial properties and did not affect the proliferation of rabbit mesenchymal stem cells (MSCs).

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The effect of antibacterial ingredients and coating microstructure on the antibacterial properties of plasma sprayed hydroxyapatite coatings

Cited by 16 publications

References 19 publications

Bioactive Coating on Ti Alloy with High Osseointegration and Antibacterial Ag Nanoparticles

Bioactive Coating on Ti Alloy with High Osseointegration and Antibacterial Ag Nanoparticles

Bioactive surface modifications through thermally sprayed hydroxyapatite composite coatings: a review of selective reinforcements

Mussel-Inspired Carboxymethyl Chitosan Hydrogel Coating of Titanium Alloy with Antibacterial and Bioactive Properties

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