The Effect of Antihypertensive of Tali’s Bamboo Shoot Ethanol Extract (Gigantochloa apus (Schult.&Schult.F.)) to Male White Rats Sprague Dawley

Abstract

Tali bamboo shoot is one of plants empirically used by the society as antihypertensive. Chemical compounds such as flavonoid, phenolic, saponins and tannins contained in Tali bamboo shoot are suspected to have antihypertensive effect. This research aimed to determine the effective dose of Tali bamboo shoot ethanol extract as a prevention of blood pressure increase in male rats with hypertension using Tail Cuff method to male rats Sprague Dawley. Rats were divided into 5 groups: negative control group (CMC Na 1%), positive control group (Hydrochlorothiazide), Tali bamboo shoot ethanol extract group with dose of 40 mg/kg rat body weight, dose of 80 mg/kg rat body weight group, and dose of 160 mg/kg rat body weight group. Tali bamboo shoot ethanol extract of dose 40 mg/kg is the most effective to decrease blood pressure to male white rats Sprague-Dawley compared to other extract doses.