Tali bamboo shoot is one of plants empirically used by the society as antihypertensive. Chemical compounds such as flavonoid, phenolic, saponins and tannins contained in Tali bamboo shoot are suspected to have antihypertensive effect. This research aimed to determine the effective dose of Tali bamboo shoot ethanol extract as a prevention of blood pressure increase in male rats with hypertension using Tail Cuff method to male rats Sprague Dawley. Rats were divided into 5 groups: negative control group (CMC Na 1%), positive control group (Hydrochlorothiazide), Tali bamboo shoot ethanol extract group with dose of 40 mg/kg rat body weight, dose of 80 mg/kg rat body weight group, and dose of 160 mg/kg rat body weight group. Tali bamboo shoot ethanol extract of dose 40 mg/kg is the most effective to decrease blood pressure to male white rats Sprague-Dawley compared to other extract doses.
Tali bamboo shoot is young shoot of bamboo potential to treat several diseases, one of them is hypertension. The aim of this study was to qualitatively identify chemical compounds and to determine antihypertensive activity of Tali bamboo ethanol extract. Extraction method applied in this experiment was maceration using ethanol 70 percent solvent. Qualitative identification toward Tali bamboo shoot powder and extract conducted using chemical reactor. Antihypertensive examination used male white rats Sprague-Dawley divided into 5 groups 5 rats each. Group I negative control (CMC Na 1percent), group II: positive control (Hydrochlorothiazide), Group III: Tali bamboo ethanol extract dose 40 mg/Kg rat body weight, Group IV: dose 80 mg/Kg rat body weight, and group V: dose 160 mg/Kg rat body weight. The results of study indicate that Tali bamboo shoot powder and ethanol extract contain flavonoid, phenolic, saponins and tannins. Tali bamboo shoot ethanol extract indicated decrease of systolic blood pressure activity in male white rats Sprague-Dawley at dose of 40 mg/Kg rat body weight, 80 mg/Kg rat body weight dan rat 160 mg/Kg body weight.
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