The effect of astaxanthin on allergic contact dermatitis in response to hair dye containing p-phenylenediamine

Trakanwittayarak, Suphattra; Meephansan, Jitlada

doi:10.1684/ejd.2019.3654

Cited by 3 publications

(11 citation statements)

References 7 publications

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“…Nine clinical trials examined the effects of various forms of herbal products, such as fresh herbs, creams, capsules, solutions, emulsions, injections, and soaps on CD. Among them, 5 studies evaluated the therapeutic measures ( 10 , 15 , 18 , 21 , 22 ) and 4 studies evaluated the preventive measures on CD ( 16 , 17 , 19 , 20 ).…”

Section: Resultsmentioning

confidence: 99%

“…In 5 studies, eligible participants were allocated into two groups (intervention and control) ( 10 , 15 , 18 , 21 , 22 ) whereas in 4 studies, the intervention and control were used in two different areas of the same body ( 16 , 17 , 19 , 20 ).…”

Section: Resultsmentioning

confidence: 99%

“…To show the effect of product, measurement of biomarkers was used in 2 studies ( 15 , 21 ) while in 7 studies clinical sign scoring system was applied ( 10 , 16 – 20 , 22 ).…”

Section: Resultsmentioning

confidence: 99%

“…Among the articles reviewed in this manuscript, four studies evaluated the side effects of herbal medicines ( 10 , 17 , 18 , 20 ), while two studies reported the side effects. Since using herbal products itself may cause contact dermatitis and side effects, this subject has been neglected ( 17 , 18 ).…”

Section: Resultsmentioning

confidence: 99%

“…Three studies have been performed on ACD ( 15 , 20 , 21 ), three studies on ICD ( 16 , 17 , 22 ), and three studies on both ( 10 , 18 , 19 ). In addition, in five studies, Patch tests were used to create dermatitis, having the advantage of differentiating between different types of CD ( 16 , 17 , 19 – 21 ).…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Effects of Herbal Medicines on the Prevention and Treatment of Contact Dermatitis: A Systematic Review

Rastegar¹,

Heydarirad²,

Aryanian³

et al. 2022

ijph

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Background: Contact dermatitis (CD) is a common inflammatory disease of the skin. CD has a complex and multifaceted treatment, and one of the main components of CD treatment is inflammation management. We summarized the clinical trials exploring the effects of herbal medicine on patients with CD. Methods: A systematic review was performed by searching four databases. Clinical trials in English investigating the effect of herbal medicines on CD prevention and treatment published from 2010 to 2020 were reviewed. This study was conducted based on the PRISMA guidelines. Results: Nine clinical trials examining the effects of herbs on CD were identified. A total of 450 patients participated in these studies. Herbal medicines used in the reviewed studies were in various forms. Almost all the studies showed that these herbs were useful in preventing and treating CD. Regarding the side effects of the herbal medicines, few complications such as erythema and papules as well as positive chronotropic effects were reported. Conclusion: Evidence showed that herbal medicines were effective in preventing and treating CD by reducing the inflammation level and increasing antioxidant defense. However, the number of clinical trials was low to draw definitive conclusions. Moreover, the studies were not homogeneous and differed regarding methodology, evaluation tools, and quality. Also, in these studies, the interactions and safety of the herbal medicines were not considered adequately. Therefore, well-designed evidence is required to draw definitive conclusions in this regard.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…To show the effect of product, measurement of biomarkers was used in 2 studies ( 15 , 21 ) while in 7 studies clinical sign scoring system was applied ( 10 , 16 – 20 , 22 ).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Effects of Herbal Medicines on the Prevention and Treatment of Contact Dermatitis: A Systematic Review

Rastegar¹,

Heydarirad²,

Aryanian³

et al. 2022

ijph

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Beneficial effects of astaxanthin in cosmeceuticals with focus on emerging market trends

Siahaan

Pangestuti

Pratama

et al. 2021

Global Perspectives on Astaxanthin

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Dermatological adverse effects of hair dye use: A narrative review

Palaniappan

Karthikeyan

Shanmugam

2023

IJDVL

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Hair dyeing is a popular practice dating back to ancient Egyptian times. Initially, hair dye use was restricted to concealing grey and white hairs of the elderly population. However, in recent times, its use is common among the younger generation as a fashion statement. Hair dye contact dermatitis is a common dermatological condition encountered by dermatologists. It is a delayed type of hypersensitivity reaction that commonly affects the scalp and the vicinity of hair line and neck. Para-phenylenediamine (PPD), a synthetic aromatic amine is the most common allergen specifically implicated in hair dye contact dermatitis. Para-phenylenediamine was announced as the allergen of the year in 2006 by the American Contact Dermatitis Society. Contact allergy to para-phenylenediamine can occur in 0.1–2.3% of the general population. Epicutaneous patch testing is the gold standard test for the diagnosis of hair dye contact dermatitis. However, para-phenylenediamine carries a risk of cross-sensitivity and co-sensitization to other allergens. Apart from contact dermatitis, hair dye use is also associated with various other cutaneous adverse effects such as pigmentary changes, hair loss, skin malignancies and autoimmune disorders. Due to the various adverse effects associated with hair dye use, it is prudent to look for safer alternatives to allergenic hair dyes. In this article, we review the epidemiology, cutaneous and systemic adverse effects associated with hair dye use, patch testing, preventive strategies to minimize the risk of hair dye contact dermatitis, and treatment aspects.

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The effect of astaxanthin on allergic contact dermatitis in response to hair dye containing p-phenylenediamine

Cited by 3 publications

References 7 publications

Effects of Herbal Medicines on the Prevention and Treatment of Contact Dermatitis: A Systematic Review

Effects of Herbal Medicines on the Prevention and Treatment of Contact Dermatitis: A Systematic Review

Beneficial effects of astaxanthin in cosmeceuticals with focus on emerging market trends

Dermatological adverse effects of hair dye use: A narrative review

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