The effect of circuit resistance training on plasma levels of amino acids, alpha-hydroxybutyrate, mannose, and urinary levels of glycine conjugated adducts in obese adolescent boys

Rasooli, Seyed Ali; Fathi, Rozita; Golzar, Farhad Ahmadi-Kani; Baghersalimi, Masoumeh

doi:10.1139/apnm-2020-0171

Cited by 7 publications

(11 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After excluding 1080 records due to their irrelevance to the research question, 1657 were considered eligible for full‐text assessment (Figure 1). A total of 116 articles 24–139 describing 114 independent trials were included in this systematic review and meta‐analysis with 23 articles examining children or adolescents, 24–46 30 articles examining young adults, 47–76 38 articles examining middle‐aged adults,…”

Section: Resultsmentioning

confidence: 99%

Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta‐analysis

et al. 2022

View full text Add to dashboard Cite

To systematically review and analyze the effects of resistance-based exercise programs on body composition, regional adiposity, and body weight in individuals with overweight/obesity across the lifespan. Using PRISMA guidelines, randomized controlled trials were searched in nine electronic databases up to December 2020. Meta-analyses were performed using random-effects model. One-hundred sixteen articles describing 114 trials (n = 4184 participants) were included. Interventions involving resistance training and caloric restriction were the most effective for reducing body fat percentage (ES = À3.8%, 95% CI: À4.7 to À2.9%, p < 0.001) and wholebody fat mass (ES = À5.3 kg, 95% CI: À7.2 to À3.5 kg, p < 0.001) compared with groups without intervention. Significant results were also observed following combined resistance and aerobic exercise (ES = À2.3% and À1.4 kg, p < 0.001) and resistance training alone (ES = À1.6% and À1.0 kg, p < 0.001) compared with no training controls. Resistance training alone was the most effective for increasing lean mass compared with no training controls (ES = 0.8 kg, 95% CI: 0.6 to 1.0 kg, p < 0.001), whereas lean mass was maintained following interventions involving resistance training and caloric restriction (ES = $ À 0.3 kg, p = 0.550-0.727). Results were consistently observed across age and sex groups (p = 0.001-0.011). Reductions in regional adiposity and body weight measures were also observed following combined resistance and aerobic exercise and programs including caloric restriction (p < 0.001). In conclusion, this study provides evidence that resistance-based exercise programs are effective and should be considered within any multicomponent therapy program when caloric restriction is utilized in individuals with overweight or obesity.

show abstract

Section: Resultsmentioning

confidence: 99%

Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta‐analysis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Of the 1495 articles screened after duplicates were removed, 55 met our inclusion criteria (eTable 1 in Supplement 1). Figure 1 illustrates the identification, screening, and inclusion process. The Cohen κ statistic for interrater reliability was 0.84 (95% CI, 0.72 to 0.96).…”

Section: Resultsmentioning

confidence: 99%

“…Baseline characteristics of participants are presented in eTable 1 in Supplement 1. Most studies were RCTs, but 8 were RCTs with no control group . Although most studies included both boys and girls in their samples, 11 studies included only boys and 9 included only girls .…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Exercise and Insulin Resistance Markers in Children and Adolescents With Excess Weight

García-Hermoso,

López-Gil,

Izquierdo

et al. 2023

JAMA Pediatr

View full text Add to dashboard Cite

ImportanceAlthough benefits have been reported for most exercise modalities, the most effective exercise approaches for reducing insulin resistance in children and adolescents with excess weight and the optimal exercise dose remain unknown.ObjectiveTo compare exercise training modalities and their association with changes in insulin resistance markers among children and adolescents with excess weight and to establish the optimal exercise dose.Data SourcesFor this systematic review and network meta-analysis, 6 electronic databases (PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Scopus, Web of Science, and CINAHL) were searched for studies from inception to April 1, 2023.Study SelectionRandomized clinical trials (ie, randomized controlled trials and randomized trials without a control group) were included if they reported outcomes associated with aerobic training, resistance training, high-intensity interval training (HIIT), or a combination of these interventions.Data Extraction and SynthesisData extraction for this systematic review was conducted following a network meta-analysis extension of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guideline. Effect sizes were calculated as the mean difference (MD) with 95% CI using random-effects inverse-variance models with the Hartung-Knapp-Sidik-Jonkman method. The hierarchy of competing interventions was defined using the surface under the cumulative ranking curve. The Cochrane Risk-of-Bias tool, version 2 (RoB2), was used to independently assess the risk of bias of the included studies. The certainty of evidence in consistent networks was assessed using the Grading of Recommendation, Assessment, Development and Evaluation approach. The study protocol was prospectively registered with PROSPERO. Data analyses were conducted between May and June 2023.Main Outcomes and MeasuresThe primary outcomes were fasting glucose, insulin, and homeostatic model assessment for insulin resistance (HOMA-IR).ResultsThis analysis included 55 studies with a total of 3051 children and adolescents (mean [SD] age, 13.5 [2.3] years; 1537 girls [50.4%] and 1514 boys [49.6%]). Exercise was associated with reductions in fasting insulin (MD, −4.38 μU/mL [95% CI, −5.94 to −2.82 μU/mL]) and HOMA-IR (MD, –0.87 [95% CI, –1.20 to –0.53]). A nonlinear association in both markers was observed, with a required minimal exercise dosage of approximately 900 to 1200 metabolic equivalent of task minutes per week, especially in children and adolescents with insulin resistance at baseline. Combination HIIT and resistance training and concurrent training were the most effective approaches for reducing insulin resistance markers. On average, the certainty of evidence varied from low to moderate.Conclusions and RelevanceThese findings underscore the role of exercise interventions in enhancing insulin resistance markers among children and adolescents with overweight and obesity. It is advisable to include resistance exercises alongside aerobic and HIIT programs for a minimum of two to three 60-minute sessions per week.

show abstract

“…Table 1 shows the characteristics of the 27 included studies, which included a sample of 1268 randomized subjects (695 were randomized to the exercise group); the mean age was 12.6 years (range 5.1-17.0 years). The authors classified the subjects as obese according to different classifications, such as BMI above the 95th percentile [21][22][23][24][25][26][27] ; BMI above the 97th percentile for age and sex alone [28][29][30][31] or in combination with body fat percentage >25% 28,32 or >34% 33 ; body fat percentage > 30% 34,35 ; BMI adjusted for age and gender 36 ; BMI ≥ 24 37,38 ; BMI ≥ 25 38,39 ; BMI ≥ 30 [40][41][42] ; BMI two standard deviations above the growth reference alone, 43 or in combination with waist circumference >80 cm 44 ; or presence of obesity according to the International Obesity Task Force cut-offs. 45 Nine studies included males only, [24][25][26][27]32,34,38,39,43 seven studies included females only, 23,31,33,35,42,44,…”

Section: Study Characteristicsmentioning

confidence: 99%

Adherence and dropout in exercise‐based interventions in childhood obesity: A systematic review of randomized trials

Guijo,

do Prado,

de Araújo

et al. 2024

Obesity Reviews

View full text Add to dashboard Cite

Our objective was to systematically examine the characteristics of exercise interventions on adherence and dropout in children and adolescents with obesity. PubMed, Embase, PsycINFO, Lilacs, Scielo, and The Cochrane Central Register of Controlled Trials and reference lists of relevant articles were searched. We included randomized controlled trials with exercise interventions for pediatric patients with obesity presenting data on dropout and/or adherence. Two reviewers screened the records independently for eligibility with disagreements being resolved by a third reviewer. Twenty‐seven studies with 1268 participants were included. Because of high heterogeneity and poor reporting of adherence, it was not possible to perform a meta‐analysis. Dropout prevalence was calculated, and subgroup analyses comparing different types of exercise and a meta‐regression with potential moderators were performed. We found a dropout rate of 13%. Subgroup analyses did not identify significant differences. The duration of the exercise presented a moderating effect on dropout, suggesting that longer exercise sessions may lead to higher dropout in children and adolescents with obesity. Because of the poor adherence data, it is not clear which exercise characteristics may moderate adherence. To improve the quality of childhood obesity care, it is mandatory that future studies present adherence data. Systematic review registration: PROSPERO CRD42021290700.

show abstract

The effect of circuit resistance training on plasma levels of amino acids, alpha-hydroxybutyrate, mannose, and urinary levels of glycine conjugated adducts in obese adolescent boys

Cited by 7 publications

References 55 publications

Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta‐analysis

Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: A systematic review and meta‐analysis

Exercise and Insulin Resistance Markers in Children and Adolescents With Excess Weight

Adherence and dropout in exercise‐based interventions in childhood obesity: A systematic review of randomized trials

Contact Info

Product

Resources

About