Abstract:Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable pulmonary disease that has extensive pulmonary and pathological adaptations. Few of these pathological changes are airway , persistent airflow limitation, finally leading to pulmonary hyperinflation. The diaphragm, which is the primary muscle of inspiration, is put through an excessive load due to the hyperinflation leading to its flattening, shortening and contraction at a mechanical disadvantage. These changes may lead to an increase… Show more
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