The effect of different training frequency on bone mineral density in older adults. A comparative systematic review and meta-analysis

Zitzmann, Anna-Lena; Shojaa, Mahdieh; Kast, Stephanie; Kohl, Matthias; Stengel, Simon von; Borucki, Diana; Gosch, Markus; Jakob, Franz; Kerschan‐Schindl, Katharina; Kladny, Bernd; Lange, U.; Middeldorf, Stefan; Peters, Stefan; Schoene, Daniel; Sieber, Cornel C.; Thomasius, Friederike; Uder, Michael; Kemmler, Wolfgang

doi:10.1016/j.bone.2021.116230

Cited by 27 publications

(15 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In parallel, against our expectation, with its close interaction of exercise parameters, the complexity of exercise might have also confounded our analysis of intensity progression and study duration. Since the methodologically correct approach for addressing this problem, i.e., trials with two exercise arms that differ only in the given component of interest (e.g., exercise frequency; [37]), was not available 4 in the domain of fracture reduction, corresponding exercise recommendations have to be derived from more dedicated metaanalyses in the area of osteoporosis [38][39][40] or fall reduction [2,41] or even better: from randomized controlled trials with similar or comparable training aims and cohorts.…”

Section: Discussionmentioning

confidence: 99%

Exercise and the prevention of major osteoporotic fractures in adults: a systematic review and meta-analysis with special emphasis on intensity progression and study duration

et al. 2022

Self Cite

View full text Add to dashboard Cite

The role of exercise in preventing osteoporotic fractures is vague, and further recommendations for optimized exercise protocols are very rare. In the present work, we provided positive evidence for exercise effects on the number of osteoporotic fractures in adults, albeit without observing any significant relevance of intensity progression or study duration. Introduction Osteoporotic fractures are a major challenge confronting our aging society. Exercise might be an efficient agent for reducing osteoporotic fractures in older adults, but the most promising exercise protocol for that purpose has yet to be identified. The present meta-analysis thus aimed to identify important predictors of the exercise effect on osteoporotic fractures in adults. Methods We conducted a systematic search of six literature databases according to the PRISMA guideline that included controlled exercise studies and reported the number of low-trauma major osteoporotic fractures separately for exercise (EG) and control (CG) groups. Primary study outcome was incidence ratio (IR) for major osteoporotic fractures. Sub-analyses were conducted for progression of intensity (yes vs. no) during the trial and the study duration (≤ 12 months vs. > 12 months). Results In summary, 11 studies with a pooled number of 9715 participant-years in the EG and 9592 in the CG were included. The mixed-effects conditional Poisson regression revealed positive exercise effects on major osteoporotic fractures (RR: 0.75, 95% CI: 0.54-0.94, p = .006). Although studies with intensity progression were more favorable, our subgroup analysis did not determine significant differences for diverging intensity progression (p = .133) or study duration (p = .883). Heterogeneity among the trials of the subgroups (I 2 ≤ 0-7.1%) was negligible. Conclusion The present systematic review and meta-analysis provided significant evidence for the favorable effect of exercise on major osteoporotic fractures. However, diverging study and exercise characteristics along with the close interaction of exercise parameters prevented the derivation of reliable recommendations for exercise protocols for fracture reductions. PROSPERO ID: CRD42021250467.

show abstract

Section: Discussionmentioning

confidence: 99%

Exercise and the prevention of major osteoporotic fractures in adults: a systematic review and meta-analysis with special emphasis on intensity progression and study duration

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…It is also not clear from the literature as to how many impact loads are needed to elicit improvements in bone strength or enhance bone mass, structure, and geometry [ 94 ], but there is evidence that 50 (5 × 10) daily multi-directional impacts (hops) eliciting loads of 2.2 to 2.7 times body weight can improve in hip BMD [ 108 ]. In terms of exercise frequency, there is evidence from clinical trials [ 109 ] and meta-analyses of randomised controlled trials (RCTs) [ 110 ] that two or more sessions per week are associated with the greatest benefits to bone. Furthermore, a meta-analysis of exercise intensity in postmenopausal women ( n = 53 trials) found that moderate to high intensity exercise was required for BMD improvement (total hip and lumbar spine BMD), with low intensity exercise and walking showing little-to-no effect [ 111 ].…”

Section: Exercise For Improving Bone Healthmentioning

confidence: 99%

Exercise to Prevent and Manage Frailty and Fragility Fractures

Dent

Daly

Hoogendijk

et al. 2023

Curr Osteoporos Rep

View full text Add to dashboard Cite

Purpose of Review This review identifies exercise-based recommendations to prevent and manage frailty and fragility fractures from current clinical practice guidelines. We also critically assess recently published literature in relation to exercise interventions to mitigate frailty and fragility fractures. Recent Findings Most guidelines presented similar recommendations that included the prescription of individually tailored, multicomponent exercise programs, discouragement of prolonged sitting and inactivity, and combining exercise with optimal nutrition. To target frailty, guidelines recommend supervised progressive resistance training (PRT). For osteoporosis and fragility fractures, exercise should include weight-bearing impact activities and PRT to target bone mineral density (BMD) at the hip and spine, and also incorporate balance and mobility training, posture exercises, and functional exercise relevant to activities of daily living to reduce falls risk. Walking as a singular intervention has limited benefits for frailty and fragility fracture prevention and management. Summary Current evidence-based clinical practice guidelines for frailty, osteoporosis, and fracture prevention recommend a multifaceted and targeted approach to optimise muscle mass, strength, power, and functional mobility as well as BMD.

show abstract

“…Der positive Effekt von Training und körperlicher Aktivität auf das Auftreten von Stürzen und sturzbedingten Frakturen konnte in der Literatur entsprechend der gewählten Evidenzkriterien belegt werden [34]. Außerdem konnte bei bestimmten Trainingsformen ein positiver Effekt auf die Muskelkraft und den Körperfettanteil [35], insbesondere bei postmenopausalen Frauen hinsichtlich des messbaren Zielparameters auch auf die Knochendichte nachge wiesen werden [36,37].…”

Section: Empfehlungen Zu Körperlichem Trainingunclassified

Kapitel Basistherapie: Kalzium, Vitamin D und K, Ernährung, Körperliches Training

et al. 2023

Self Cite

View full text Add to dashboard Cite

ZusammenfassungIn diesem Artikel wird der aktuelle Stand der DVO-Leitlinienempfehlungen zur Basistherapie vorgestellt. Die Basistherapie ist die Grundlage jeder Osteoporosebehandlung und ist auch für die Primärprävention von entscheidender Bedeutung, noch bevor die Knochenmineraldichte niedrig ist oder Frakturen auftreten. Auf der Grundlage einer aktualisierten Literaturrecherche umfasst das Kapitel Empfehlungen zu Kalzium, Vitamin D, Vitamin K und anderen Ernährungsaspekten sowie zu körperlicher Aktivität. Frühere Empfehlungen wurden überprüft und auf der Grundlage der neuen Literatur ergänzt. Die Empfehlungen für die Einnahme von Kalzium und Vitamin D, situationsabhängig entweder über die Ernährung oder über Supplemente, bleiben unverändert. Vitamin K wird nur zum Ausgleich eines Mangels empfohlen, da die Datenlage für eine Empfehlung in anderen Bereichen wie der allgemeinen Frakturprävention zu inkonsistent ist. Körperliche Aktivität hat einen positiven Effekt auf das Frakturrisiko und die Knochendichte und ist daher auch weiterhin eine wichtige Empfehlung, idealerweise im Rahmen eines angepassten, supervidierten Trainingsprogramms.

show abstract

The effect of different training frequency on bone mineral density in older adults. A comparative systematic review and meta-analysis

Cited by 27 publications

References 31 publications

Exercise and the prevention of major osteoporotic fractures in adults: a systematic review and meta-analysis with special emphasis on intensity progression and study duration

Exercise and the prevention of major osteoporotic fractures in adults: a systematic review and meta-analysis with special emphasis on intensity progression and study duration

Exercise to Prevent and Manage Frailty and Fragility Fractures

Kapitel Basistherapie: Kalzium, Vitamin D und K, Ernährung, Körperliches Training

Contact Info

Product

Resources

About