The Effect of Dopamine Secreted by the Brain into the Systemic Circulation on Prolactin Synthesis by the Pituitary gland in Ontogenesis

Nikishina, Yu. O.; Sapronova, A. Ya.; Ugrumov, M. V.

doi:10.32607/20758251-2016-8-3-111-117

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The experimental results indicate that the dopamine sensor revealed satisfactory operational characteristics, such as near-Nernst response, good reproducibility and stability. The µM-level detection limit and good selectivity make the dopamine sensor suitable for the detection of dopamine in the striatum of rat brains [10,38]. With a wide linear range, fast dynamic response and good performance in ASCF, the dopamine sensor is promising for the detection of rapid and wide changes of dopamine concentration in the nervous system when nerve impulses are generated.…”

Section: Discussionmentioning

confidence: 99%

A miniature potentiometric sensor for dopamine determination in vitro

He¹,

Li²,

Wang³

et al. 2021

Meas. Sci. Technol.

View full text Add to dashboard Cite

Electrochemical sensors can be used to detect neurotransmitters. A miniature potentiometric all-solid-state coated wire dopamine sensor was investigated in this work. Conducting polymer poly (3,4- ethylenedioxythiophene) doped with poly (styrenesulfonate) as the solid contact was electropolymerized on one end of a gold wire (diameter 0.25 mm). The conducting polymer was covered with a dopamine-selective membrane containing 12-crown-4-tetraphenylborate as a neutral carrier, 2-nitrophenyloctyl ether as a plasticizer and poly (vinyl chloride) as the membrane matrix. The dopamine sensor covered a wide linear range from 10–5 M to 10–1 M with a slope of 53.85 ± 0.93 mV/decade, while the detection limit was 5.80 ± 0.31 µM. The other characteristics of the dopamine sensor were also evaluated. The experimental results showed that the sensor operated properly within the pH range of 5.5–7.5 and displayed good selectivity, fast dynamic response, high reproducibility and long stability. In addition, the dopamine sensor was successfully applied for the detection of dopamine in artificial cerebrospinal fluid by using the standard addition method, indicating that this sensor is promising for applications in dopamine determination in neuroscientific research.

show abstract

Section: Discussionmentioning

confidence: 99%

A miniature potentiometric sensor for dopamine determination in vitro

He¹,

Li²,

Wang³

et al. 2021

Meas. Sci. Technol.

View full text Add to dashboard Cite

show abstract

Where Is Dopamine and how do Immune Cells See it?: Dopamine-Mediated Immune Cell Function in Health and Disease

Matt

Gaskill

2019

J Neuroimmune Pharmacol

201

171

View full text Add to dashboard Cite

HIV-Associated Apathy/Depression and Neurocognitive Impairments Reflect Persistent Dopamine Deficits

McLaurin¹,

Harris²,

Madormo³

et al. 2021

Cells

View full text Add to dashboard Cite

Individuals living with human immunodeficiency virus type 1 (HIV-1) are often plagued by debilitating neurocognitive impairments and affective alterations;the pathophysiology underlying these deficits likely includes dopaminergic system dysfunction. The present review utilized four interrelated aims to critically examine the evidence for dopaminergic alterations following HIV-1 viral protein exposure. First, basal dopamine (DA) values are dependent upon both brain region andexperimental approach (i.e., high-performance liquid chromatography, microdialysis or fast-scan cyclic voltammetry). Second, neurochemical measurements overwhelmingly support decreased DA concentrations following chronic HIV-1 viral protein exposure. Neurocognitive impairments, including alterations in pre-attentive processes and attention, as well as apathetic behaviors, provide an additional line of evidence for dopaminergic deficits in HIV-1. Third, to date, there is no compelling evidence that combination antiretroviral therapy (cART), the primary treatment regimen for HIV-1 seropositive individuals, has any direct pharmacological action on the dopaminergic system. Fourth, the infection of microglia by HIV-1 viral proteins may mechanistically underlie the dopamine deficit observed following chronic HIV-1 viral protein exposure. An inclusive and critical evaluation of the literature, therefore, supports the fundamental conclusion that long-term HIV-1 viral protein exposure leads to a decreased dopaminergic state, which continues to persist despite the advent of cART. Thus, effective treatment of HIV-1-associated apathy/depression and neurocognitive impairments must focus on strategies for rectifying decreases in dopamine function.

show abstract

The Effect of Dopamine Secreted by the Brain into the Systemic Circulation on Prolactin Synthesis by the Pituitary gland in Ontogenesis

Cited by 3 publications

References 23 publications

A miniature potentiometric sensor for dopamine determination in vitro

A miniature potentiometric sensor for dopamine determination in vitro

Where Is Dopamine and how do Immune Cells See it?: Dopamine-Mediated Immune Cell Function in Health and Disease

HIV-Associated Apathy/Depression and Neurocognitive Impairments Reflect Persistent Dopamine Deficits

Contact Info

Product

Resources

About